Type 2 Diabetes Mellitus With Features of Insulin Resistance Clinical Trial
Official title:
A Randomized Controlled Trial Evaluating the Effects of Electroacupuncture and Rosiglitazone Combined Therapy on Patients With Type 2 Diabetes Mellitus
Aims: To evaluate the efficacy of rosiglitazone (TZD) and electroacupuncture (EA) combined
therapy on patients with type 2 diabetes mellitus (T2DM). A randomized single-blind placebo
controlled clinical trial was used.
Methods: A total of 31 newly diagnostic type 2 diabetic patients, who fulfilled the
eligibility criteria were recruited and received various allocated interventions. They were
randomly assigned into two groups, the control group (TZD, N=15) and the experimental group
(TZD + EA, N=16). Changes in their plasma free fatty acid (FFA), glucose and insulin levels
together with their homeostasis model assessment (HOMA) indices were statistically assessed
between before and after treatment. Hypoglycemic activity (%) was also compared between
these two groups.
Expecting Results: This study will compare the hypoglycemic activity and the ability of
improving insulin resistance between the TZD and TZD+EA group. Also, the lowering effect of
the plasma FFA concentration will be investigated.
This study is compared the effect between combined therapy (EA+TZD) and drug (TZD) on the patient of type 2 DM. ;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
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