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NCT01498757 Clinical Trial

Genome-wide Association Study

Esophageal Squamous Cell Carcinoma Clinical Trial

Official title:
Genome-wide Association Study to Predict Treatment Response for Chemotherapy in Esophageal Squamous Cell Carcinoma

Clinical Trial Details — Status: Withdrawn

Administrative data
NCT number NCT01498757
Other study ID # 2011-05-076
Secondary ID
Status Withdrawn
Phase
First received
Last updated
Start date January 2012
Est. completion date July 3, 2012

Study information
Verified date May 2019
Source Samsung Medical Center
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

To explore biomarkers predictive of clinical response to Taxane/5-FU/platinum based chemotherapy in esophageal squamous cell carcinoma. To identify negative predictive markers to 5-FU/platinum/Taxane. To elucidate signal transduction pathway attributable to 5-FU/platinum/Taxane resistance. To analyze correlation between the quantity of circulating tumor cells and circulating endothelial cell precursors and treatment response to Taxane/5-FU/platinum based chemotherapy.

Recruitment information / eligibility
Status Withdrawn
Enrollment 0
Est. completion date July 3, 2012
Est. primary completion date June 2012
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Histological confirmed esophageal squamous cell carcinoma

- Patients treated with Taxane or 5-FU or platinum based chemotherapy.

- provision of a signed written informed consent.

Exclusion Criteria:

- patients not signed written informed consent.

- patient unacceptable for study in the judgement of the investigator.

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Korea, Republic of Samsung medical Center Seoul

Sponsors (1)
Lead Sponsor Collaborator
Samsung Medical Center

Country where clinical trial is conducted

Korea, Republic of, 

Outcome
Type Measure Description Time frame Safety issue
Primary Biomarkers predictive Biomarkers predictive of clinical response to Taxane or 5-fluorouracil or platinum based chemotherapy. 24months
See also
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