Hypertension, Resistant to Conventional Therapy Clinical Trial
Official title:
Prevalence of Primary Aldosteronism and Status of Renin-Angiotensin System in Resistant Hypertension:An Observational Study in China
| NCT number | NCT01459042 |
| Other study ID # | 19830409 |
| Secondary ID | |
| Status | Completed |
| Phase | N/A |
| First received | October 21, 2011 |
| Last updated | October 24, 2011 |
| Start date | January 2010 |
| Verified date | October 2011 |
| Source | Shanghai Jiao Tong University School of Medicine |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | China: Ethics Committee |
| Study type | Observational |
Recent studies indicate that primary aldosteronism (PA) is a much more common cause of hypertension than had been demonstrated historically. In patients with resistant hypertension, the prevalence of PA from different clinics worldwide is about 10-20%. As has been no such data in China, the investigators are conducting a PA study in different province of China to evaluate the prevalence of PA in patients with resistant hypertension.
| Status | Completed |
| Enrollment | 2000 |
| Est. completion date | |
| Est. primary completion date | October 2011 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 18 Years to 65 Years |
| Eligibility |
Inclusion Criteria: - patients with resistant hypertension - age 18-65 years Exclusion Criteria: - known cause of hypertension - heart failure - renal dysfunction - Stroke, transient ischaemic attack or myocardial infarction in the past 6 months - cirrhosis - pregnancy - undertreatment of glucocorticoid |
Observational Model: Ecologic or Community, Time Perspective: Cross-Sectional
| Country | Name | City | State |
|---|---|---|---|
| China | Dep.endocrinology of Shanghai Ruijin Hospital, Shanghai Jiaotong university school of medcine | Shanghai | Shanghai |
| Lead Sponsor | Collaborator |
|---|---|
| Shanghai Jiao Tong University School of Medicine |
China,
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