Complications of Diabetes Mellitus Clinical Trial
Official title:
Acute Changes in Intraocular Cytokines After Intravitreal Bevacizumab
Purpose: To evaluate the acute changes in intraocular cytokines after intravitreal
bevacizumab (IVB) in proliferative diabetic retinopathy.
Design: Prospective, open-label, controlled, randomized interventional clinical trial.
Participants: Twenty eyes of 28 consecutive patients who are scheduled for pars plana
vitrectomy (ppV) for proliferative diabetic retinopathy were prospectively enrolled.
Methods: All patients were randomly assigned to receive IVB either at 2 or 7 days before
ppV. Aqueous humor samples were taken from anterior chamber just before IVB and at the time
of surgery. Multiplex cytokine array were used to assay various cytokines
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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