Continuous Versus Conventional Volume Management During CRRT (Continuous Renal Replacement Therapy)

Continuous Renal Replacement Therapy Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01405092
• Other study ID #: #09-097
• Status: Completed
• Phase: N/A
• First received: July 28, 2011
• Last updated: August 7, 2012
• Start date: April 2010
• Est. completion date: August 2012

Study information

• Verified date: August 2012
• Source: Dallas VA Medical Center
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Federal Government
• Study type: Interventional

Clinical Trial Summary

Use of on-line blood volume monitoring during continuous renal replacement therapy can improve volume management in acute kidney injury patients requiring renal replacement

Recruitment information / eligibility

• Status: Completed
• Enrollment: 28
• Est. completion date: August 2012
• Est. primary completion date: August 2012
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 21 Years and older

Eligibility

Inclusion Criteria:

• Patients with kidney injury requiring continuous renal replacement therapy and volume removal

Exclusion Criteria:

• unable to provide or obtain patient consent

• not expected to survive 48 hours

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Supportive Care

Related Conditions & MeSH terms

• Continuous Renal Replacement Therapy

Intervention

Device:
• use of continuous renal replacement machine for renal replacement
usual care with volume removal during continuous renal replacement therapy
• use of blood volume monitoring device in conjunction with machine used for continuous renal replacement to assess and determine volume removal
blood volume monitoring device, Critline, Hemametric, USA, will be used in conjunction with continuous renal replacement to determine rate of volume removal

Locations

Country	Name	City	State
United States	Dallas VA Medical Center	Dallas	Texas

Sponsors (1)

Lead Sponsor	Collaborator
Dallas VA Medical Center

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	compare number of hypotensive events in treatment versus control arms	compare the number of hypotensive events during use of crit-line monitor over 24 hour period versus during control 24 hour period	24 hour for each arm	Yes