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Diagnosis Accuracy of Hemoconcentration to Detect Hypovolemia During CRRT

Intensive Care Unit Clinical Trial

Official title:
Is Variation of Plasmatic Protein Concentration During Continuous Renal Replacement Therapy Predictive of Hypovolemia in Intensive Care Unit?

Clinical Trial Summary

The aim of the study is to analyze if blood protein concentration variation during continuous renal replacement therapy (CRRT) with fluid removal can predict a decrease of 15 % of cardiac index in intensive care unit (ICU) patients. Blood protein concentration, clinical data describing hemodynamic status (providing data from Pulsion medical system PiCCO2 ® monitoring), including preload dependency evaluation with passive leg raising, are collected at different times: before initiation of fluid removal, and after the first episode of hypotension or one hour after initiation of fluid removal.

Clinical Trial Description

The aim of the study is to analyze if blood protein concentration variation during continuous renal replacement therapy (CRRT) with fluid removal can predict a decrease of 15 % of cardiac index in intensive care unit (ICU) patients. Blood protein concentration, clinical data describing hemodynamic status (providing data from Pulsion medical system PiCCO2 ® monitoring), including preload dependency evaluation with passive leg raising, are collected at different times: before initiation of fluid removal, and after the first episode of hypotension or one hour after initiation of fluid removal. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03144349
Study type Observational [Patient Registry]
Source Hopital Louis Pradel
Contact Matthias Jacquet-Lagèze, M.D., M.Sc.
Phone +33 6 89 99 59
Email matthias.jl@gmail.com
Status Recruiting
Phase
Start date December 2016
Completion date December 2019
View Details
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