Dose-Dependent Effect of Early Antiplatelet Therapy in Acute Ischemic Stroke

Test the Efficacy of Antiplatelet Regimes in Acute Stroke Clinical Trial

Official title:

Dose-Dependent Effect of Early Antiplatelet Therapy in Acute Ischemic Stroke

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01273935
• Other study ID #: MevesASS01
• Status: Completed
• Phase: N/A
• First received: January 10, 2011
• Last updated: January 10, 2011
• Start date: January 2010
• Est. completion date: December 2010

Study information

• Verified date: January 2010
• Source: Ruhr University of Bochum
• Contact: n/a
• Is FDA regulated: No
• Health authority: Germany: Ethics Commission
• Study type: Observational

Clinical Trial Summary

The aim of this study is to evaluate the low-response prevalence of early antiplatelet therapy and to test the influence of different aspirin dosages in patients with acute ischemic strokes (AIS).

Description:

Antiplatelet agents are important therapeutic options in treating patients with acute ischemic strokes to prevent recurrent ischemic events or death. The aim of this study was to evaluate the low-response prevalence of early antiplatelet therapy and the influence of different aspirin dosages in patients with acute ischemic strokes (AIS).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 400
• Est. completion date: December 2010
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• suspected acute cerebrovascular ischemic events and patients who were admitted to the stroke unit where antiplatelet therapy was initiated

Exclusion Criteria:

• severe liver disorders, current gastrointestinal disorders, congestive heart failure, life-threatening malignancies and a personal or family history of bleeding disorders

Study Design

Observational Model: Case-Only, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Stroke
• Test the Efficacy of Antiplatelet Regimes in Acute Stroke

Locations

Country	Name	City	State
Germany	Department of Neurology, St. Josef - Hospital, Ruhr-University	Bochum	NRW

Sponsors (1)

Lead Sponsor	Collaborator
Ruhr University of Bochum

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Result of platelet function test	Aggregometry result of antiplatelet therapy		No