Autosomal Dominant Polycystic Kidney Disease Clinical Trial
Official title:
Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP) II
The Division of Kidney Urology and Hematology Disease (DKUHD) of the National Institute of
Diabetes and Digestive and Kidney Diseases (NIDDK) funded a cooperative agreement (UO1) for a
consortium of participating clinical centers (PCCs) and a data coordinating and imaging
analysis center (DCIAC) to develop and implement studies to test whether imaging techniques
can provide accurate and reproducible markers of progression of renal disease in patients
with polycystic kidney disease.
The awarded participating clinical centers are Emory University, University of Kansas, and
Mayo Foundation (with a subcontract to the University of Alabama). The awarded DCIAC is
Washington University in St. Louis. Due to the relocation of the DCIAC P.I. from Washington
University to the University of Pittsburgh, the DCIAC for CRISP II is located at the
University of Pittsburgh.
The goal of the CRISP Study is to conduct a prospective, longitudinal trial to evaluate the accuracy and validity of magnetic resonance imaging to determine disease progression in ADPKD defined as a change in both renal and renal cyst volumes and renal function over time. ;
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