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Autologous Mesenchymal Stem Cell (MSC) Transplantation in MS

Relapsing-Remitting Multiple Sclerosis Clinical Trial

Official title:
A Phase I Study to Assess the Feasibility, Safety, and Tolerability of Autologous Mesenchymal Stem Cell Transplantation in Patients With Relapsing Forms of Multiple Sclerosis

Clinical Trial Summary

The study is an investigator-run, open-label Phase 1 safety study of autologous mesenchymal stem cell transplantation, involving approximately 24 ambulatory participants with relapsing forms of MS (approximately equal numbers with relapsing-remitting and secondary progressive/ progressive relapsing MS) and evidence of involvement of the anterior afferent visual system.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

  • Multiple Sclerosis
  • Multiple Sclerosis, Chronic Progressive
  • Multiple Sclerosis, Relapsing-Remitting
  • Progressive Relapsing Multiple Sclerosis
  • Relapsing-Remitting Multiple Sclerosis
  • Sclerosis
  • Secondary Progressive Multiple Sclerosis
Clinical Trial Details
NCT number NCT00813969
Study type Interventional
Source The Cleveland Clinic
Contact
Status Completed
Phase Phase 1
Start date March 2011
Completion date May 2014
View Details
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