Proliferative Diabetic Retinopathy Clinical Trial
Official title:
Vitreous Levels of Patients With Proliferative Diabetic Retinopathy.
Verified date | August 2008 |
Source | National Taiwan University Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | Taiwan: Department of Health |
Study type | Observational |
Fractalkine (FKN) is a chemoattractant and adhesion molecule for leukocytes. Angiogenic effect of FKN also has been reported. We investigate FKN-mediated angiogenesis in ocular angiogenic disorders.
Status | Completed |
Enrollment | 30 |
Est. completion date | December 1998 |
Est. primary completion date | December 1998 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - clinical diagnosis of proliferative diabetic retinopathy. - who will receive vitrectomy for treatment of disease. Exclusion Criteria: - previous ocular surgical history. - history of uveitis - history of ocular trauma. |
Observational Model: Case Control, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Taiwan | The department of ophthalmology, National Taiwan University Hospital | Taipei |
Lead Sponsor | Collaborator |
---|---|
National Taiwan University Hospital |
Taiwan,
Aiello LP, Avery RL, Arrigg PG, Keyt BA, Jampel HD, Shah ST, Pasquale LR, Thieme H, Iwamoto MA, Park JE, et al. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med. 1994 Dec 1;331(22):1480-7. — View Citation
Petrovic MG, Korosec P, Kosnik M, Hawlina M. Vitreous levels of interleukin-8 in patients with proliferative diabetic retinopathy. Am J Ophthalmol. 2007 Jan;143(1):175-6. Epub 2006 Sep 1. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Vitreous levels and serum levels of Fractalkine, VEGF, other growth factor. | vitreous sample collected on vitrectomy | Yes |
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