Catheter Related Bloodstream Infection Clinical Trial
Official title:
A Crossover Intervention Trial Evaluating the Efficacy of a Chlorhexidine-Impregnated Sponge (BIOPATCH®) to Reduce Catheter-Related Bloodstream Infections in Hemodialysis Patients
There are currently no published data on the efficacy of the chlorhexidine-impregnated foam
dressing to reduce catheter-related bloodstream infections (BSI) in hemodialysis patients.
The researchers perfomed a cross-over intervention trial on patients who were dialyzed
through central venous catheters at two outpatient dialysis centers were enrolled. The use
of a chlorhexidine-impregnated foam dressing was incorporated into the catheter care
protocol during the intervention period. A nested cohort study of all patients who received
the foam dressing was also conducted to determine independent risk factors for development
of BSI.
The primary outcomes were the catheter-related bloodstream infection rates in the
intervention and control groups. Secondary outcomes include the clinical sepsis rates
between the two groups and risk factors for development of bloodstream infection despite the
use of the foam dressing.
n/a
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment
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| Completed |
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Phase 4 | |
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