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Clinical Trial Summary

- Safety and efficacy of letrozole 2.5 mg/day monotherapy as second-line endocrine therapy in postmenopausal patients with advanced breast cancer who received previous anti-estrogen treatment

- To investigate changes in blood drug concentrations and blood hormone kinetics.

- To investigate gene polymorphisms of CYP2A6, an enzyme involved in the metabolism of letrozole


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT00237198
Study type Interventional
Source Novartis
Contact
Status Completed
Phase Phase 2
Start date March 2004

See also
  Status Clinical Trial Phase
Completed NCT00237211 - Study of High-dose Letrozole Therapy in Postmenopausal Patients With Breast Cancer Phase 2
Completed NCT00247663 - Extension Study of 1.0mg Dose Letrozole Therapy in Postmenopausal Patients With Breast Cancer Phase 2