Rosiglitazone And Plaque Study for Type 2 Diabetes Mellitus

Non-insulin-dependent Diabetes Mellitus Clinical Trial

Official title:
Rosiglitazone and Plaque Study: A 12 Month Randomised, Double-blind, Placebo-controlled, Magnetic Resonance Imaging Study to Evaluate the Effect of Rosiglitazone on the Structure and Composition of Carotid Atherosclerotic Plaques in Subjects With Type 2 Diabetes Mellitus and Coexisting Vascular Disease or Hypertension

Status Completed

Clinical Trial Summary

This is a phase IIIb, randomised, double blind, placebo controlled, study in patients with type 2 diabetes mellitus and coexisting vascular disease or hypertension. The total duration of the study will be approximately 60 weeks. The aim of this study is to examine the potential beneficial effects of rosiglitazone on carotid atheroma in patients with type 2 diabetes mellitus and coexisting vascular disease or hypertension. It is hypothesised that treatment with rosiglitazone will lead to an decrease in plaque size. In addition, it is hoped that rosiglitazone will have a positive effect on plaque composition and stability.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Diabetes Mellitus
Diabetes Mellitus, Type 2
Non-insulin-dependent Diabetes Mellitus

Clinical Trial Details

NCT number	NCT00231387
Study type	Interventional
Source	GlaxoSmithKline
Contact
Status	Completed
Phase	Phase 3
Start date	September 2002
Completion date	May 2005

View Details

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