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Dextromethorphan in Treating Patients With Fatigue Caused by Cancer

Fatigue Clinical Trial

Official title:
A Pilot Trial to Evaluate the Effects of Dextromethorphan in Patients Suffering From Cancer-Related Fatigue

Clinical Trial Summary

RATIONALE: Dextromethorphan may help relieve fatigue in patients with cancer.

PURPOSE: This clinical trial is studying how well dextromethorphan works in treating patients with fatigue caused by cancer.

Clinical Trial Description

OBJECTIVES:

Primary

- Assess the effects of dextromethorphan hydrobromide in patients with cancer-related fatigue.

Secondary

- Correlate the changes in cancer-related fatigue with the levels of plasma homocysteine versus red blood cell folate.

OUTLINE: This is a multicenter, open-label, pilot study.

Patients receive oral dextromethorphan hydrobromide 3 times a day on days 1-7. Treatment repeats weekly for up to 3 weeks in the absence of disease progression or unacceptable toxicity.

PROJECTED ACCRUAL: A total of 30 patients will be accrued for this study. ;

Study Design

Masking: Open Label, Primary Purpose: Supportive Care

Related Conditions & MeSH terms

  • Fatigue
  • Unspecified Adult Solid Tumor, Protocol Specific
  • Unspecified Childhood Solid Tumor, Protocol Specific
Clinical Trial Details
NCT number NCT00176540
Study type Interventional
Source Rutgers, The State University of New Jersey
Contact
Status Terminated
Phase N/A
Start date October 2003
Completion date August 2007
View Details
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