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NCT ID: NCT06452251 Completed - Clinical trials for Vitamin D Deficiency

Vitamin-D Insufficiency and Implants

Start date: January 1, 2022
Phase:
Study type: Observational

Vitamin D is important for bone health, immune function, and inflammation, along with dental implant success. The study aimed to assess bone markers and cytokine levels in patients with and without vitamin D insufficiency to better understand the effects of vitamin D levels on dental implant integration. The study included 42 patients in 2 groups; with insufficient (Group IN-S; n=21) and sufficient (Group S; n=21) levels of vitamin D. Bone remodelling, proinflammatory and antiinflammatory markers were analyzed in bone and peri-implant crevicular fluid (PICF) using enzyme-linked immunosorbent assay (ELISA) and results were reported as concentration and total amount.

NCT ID: NCT06449040 Completed - Clinical trials for Cutaneous Leishmaniasis, American

Treatment of Cutaneous Leishmaniasis With Liposomal Amphotericin B in the Elderly

Start date: March 1, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

A randomized controlled pilot trial with the aim of identifying the dose of liposomal amphotericin B associated with the highest cure rate in Cutaneous Leishmaniasis (CL). We selected 28 patients of both sexes, aged 60 years or older, diagnosed with CL and confirmed by detection of L. braziliensis DNA. The groups were treated with different total doses of medication: G1: 12 mg/kg; G2: 18mg/kg; G3: 24 mg/kg. Clinical and laboratory evaluations were carried out during the period of 180 days (D0, D15, D30, D60, D120, D150 and D180).

NCT ID: NCT06447896 Completed - Clinical trials for Cardiovascular Autonomic Neuropathy

Clinical Validation of a Cardiovascular Autonomic Nervous Function Multi-Parameter Evaluation System

CARTS
Start date: March 11, 2011
Phase: N/A
Study type: Interventional

This is a open-label, randomized, paired design, multicenter study of the Cardiovascular Autonomic Nervous Function Multi-Parameter Evaluation System (R6000) for evaluating cardiovascular autonomic neuropathy. R6000 is novel intellectual diagnostic device for cardiovascular autonomic reflex tests and heart rate variability analysis. A total of 85 subjects will be enrolled in trial Ⅰ and 150 subjects will be enrolled in trial Ⅱ. In trial Ⅰ, subjects will be randomized to two groups, one of which will receive test by the tested device first and the other one will be tested by conventional blood pressure kit. The primary objective of this clinical trial is to evaluate the effectiveness of the Cardiovascular Autonomic Nervous Function Multi-Parameter Evaluation System. The secondary objective is to evaluate the safety of the cardiovascular autonomic testing system and stability.

NCT ID: NCT06445387 Completed - Clinical trials for Percutaneous Coronary Intervention

Pain During Femoral Sheath Removal in Patients Undergoing Percutaneous Coronary Intervenion

Start date: July 12, 2021
Phase: N/A
Study type: Interventional

It is to examine the effect of virtual reality and ice application on the pain level due to femoral sheath extraction.

NCT ID: NCT06444386 Completed - Clinical trials for Cardiac Resynchronization Therapy

ECGi of SyncAV With MultiPoint Pacing

Start date: September 29, 2021
Phase:
Study type: Observational

The objective of this clinical study was to evaluate the impact of Multipoint Pacing (MPP) and SyncAV programming on ventricular electrical activation time and activation sequence using noninvasive electrocardiographic imaging (ECGi) in patients receiving cardiac resynchronization therapy (CRT).

NCT ID: NCT06443814 Completed - Metabolic Syndrome Clinical Trials

Trial of Meditation for Cardiometabolic Disease in Older Black Women

Start date: July 2001
Phase: Phase 2
Study type: Interventional

This randomized controlled trial compared the efficacy of stress reduction with meditation to a health education (HE) group in 201 older African American women over a one-year study period. They were randomly allocated to either of two behavioral treatment groups-1) the Transcendental Meditation (TM( program or 2) a health education (HE) program. Women participants were recruited, tested, and instructed at two clinical sites: Washington, DC and Atlanta, GA. Outcome measures were carotid intima medial thickness, lipid profile, glucose and insulin resistance, and behavioral factors.

NCT ID: NCT06442163 Completed - Clinical trials for Obesity Hypoventilation Syndrome (OHS)

Average Volume-assured Pressure Support as Rescue Therapy in Obesity Hypoventilation Syndrome

AVAPS
Start date: May 12, 2020
Phase: N/A
Study type: Interventional

It remains unclear whether CPAP therapy should be prescribed if significant hypoxemia persists during CPAP titration, despite optimization of upper airway obstructive events, if maximum CPAP pressure is reached. The goal was to examine the effects of 6 months of home AVAPS therapy in patients with obesity hypoventilation syndrome as a potential option for patients who failed CPAP titration due to persistent hypoxemia.

NCT ID: NCT06440265 Completed - Clinical trials for Intensive Care Unit Acquired Weakness

Validity and Reliability of Korean Version of AM-PAC Inpatient Short Form (Low Function) in Critically Ill Patients

AM-PAC
Start date: March 31, 2023
Phase:
Study type: Observational

The Activity Measure for Post Acute Care (AM-PAC) inpatient short form (low function) evaluates the level of assistance a patient requires another person to provide for distinct functional mobility and daily activities. The objective of the study was to translate and cross-culturally adapt the AM-PAC (low function) into Korean version and assess its reliability and validity . Independent raters assessed 38 patients from ICU using the Korean version of AM-PAC, respectively. Intra-class correlation coefficients (ICCs) and Bland-Altman's plots were used to evaluate reliability, and Cronbach's alpha for internal consistency. Validity was evaluated using Spearman's correlation analysis with other physical function assessment tools (functional status score for the ICU(FSS-ICU), Medical Research Council-sum score(MRC-SS), hand grip strength) and other unrelated factors (body mass index, glucose level).

NCT ID: NCT06437717 Completed - Clinical trials for Chronic Rhinosinusitis (Diagnosis)

Role of Nanoemulsified Sesame Oil in Post-operative Care After Endoscopic Sinus Surgery

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

The goal of our thesis is to design, develop and characterize a novel thermodynamically stable NE by spontaneous method intended for topical use. Subsequently, appraisal of nanoemulsified sesame oil formulation has been performed on the post-operative symptoms in CRS patients who have undergone ESS (endoscopic sinus surgery) combined with different types of nasal irrigation which may affect formulation efficacy.

NCT ID: NCT06437639 Completed - Clinical trials for Primary Open-Angle Glaucoma (POAG)

MEXIDOL® Sequential Therapy of Patients With Primary Open-angle Glaucoma (POAG)

Start date: September 15, 2023
Phase: Phase 4
Study type: Interventional

Hypothesis: The use of neurocytoprotectors helps restore the functional activity of mitochondria, improve the nervous activity of the retina and optic nerve, and stabilize the glaucomatous process.