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Bone Mass Changes in Anorexia Nervosa Patient Followed During 4 Years — AMOS  

Osteoporosis Clinical Trial

Official title:
Bone Mass Changes in Anorexia Nervosa Patient Followed During 4 Years and Relationship Between Bone Loss and Adipokines.

Clinical Trial Summary

The mechanism of bone loss in anorexia nervosa is complex. Marrow adipose tissue seems to play a role in the regulation of bone metabolism. Adipocytes secrete cytokines and adipokines that either stimulate or inhibit adjacent osteoblasts. This study consist to explore the relationship in anorexia nervosa patients with change in bone mineral density and adipokines like leptin, adiponectin and Préf-1 Bone mineral densities will be measure in 180 anorexia nervosa patients at inclusion and every two years during 6 years.It is assessed blood and urinary calcium and phosphate levels, bone remodelling markers and adipokines (leptin, adiponectin and Préf-1)

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02891356
Study type Observational
Source University Hospital, Lille
Contact Isabelle LEGROUX, MD
Email isabelle.legroux@chru-lille.fr
Status Recruiting
Phase
Start date July 2013
Completion date July 2022
View Details
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