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Osteoarthritis clinical trials

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NCT ID: NCT06164899 Recruiting - Knee Osteoarthritis Clinical Trials

Long-term Evaluation of Outcomes of Patients Undergoing Autologous Bone Marrow Concentrate Infiltration vs. Hyaluronic Acid

Start date: February 9, 2024
Phase:
Study type: Observational

This is a prospective observational study for long-term clinical evaluation (minimum 4-year follow-up) in patients treated within the research protocol "OA-bi-blind" (Double-blind randomized trial on the treatment of bilateral knee osteoarthritis: Autologous bone marrow concentrate VS. hyaluronic acid)

NCT ID: NCT06163573 Recruiting - Clinical trials for Patellofemoral Osteoarthritis

Treatment of Patellofemoral Osteoarthritis With Engineered Cartilage.

Start date: June 6, 2024
Phase: Phase 2
Study type: Interventional

The purpose of this investigator-initiated study is to assess the efficacy of treating patellofemoral osteoarthritis with an Advanced Therapy Medicinal Product (ATMP), autologous nasal chondrocyte tissue engineered cartilage (N-TEC), in comparison with a standard therapy using platelet rich plasma injections. The engineered cartilage graft is obtained by culturing expanded autologous nasal chondrocytes within a collagen type I/III membrane.

NCT ID: NCT06157723 Recruiting - Knee Osteoarthritis Clinical Trials

Economic Burden of Knee Osteoarthritis in Talavera de la Reina Health Area.

Start date: April 1, 2023
Phase:
Study type: Observational [Patient Registry]

This is a descriptive retrospective study of individuals affected with knee osteoarthritis. The aim of this study is to describe the sociodemographic and clinical characteristics of individuals diagnosed with knee osteoarthritis within a specific health area, as well as to assess the economic impact of this condition on the healthcare system. To achieve this, medical records will be reviewed, and the following data will be collected: Sociodemographic and clinical participant data. Healthcare resource use. Clinical burden. Up to 400 subjects will be enrolled in the Talavera de la Reina Health Area (Toledo, Spain).

NCT ID: NCT06154694 Recruiting - Clinical trials for Osteoarthritis of Shoulder

Glenohumeral Joint Contract Patterns in Osteoarthritic Glenoids

TSA
Start date: November 3, 2021
Phase:
Study type: Observational

Shoulder osteoarthritis (OA) is a frequent problem in our aging population and is believed to occur in up to 20% of the population. Different types of glenoid morphology are associated with shoulder OA, depending on the amount and localization of the glenoid erosion as well as the amount and direction of Humeral Head Migration. Total shoulder arthroplasty (TSA) has been shown to relieve the pain and improve joint function of patients with OA. However, several complications such as component loosening and polyethylene damage has been reported and it has been revealed that 7.3% of glenoids may show signs of asymptomatic radiographic loosening annually after primary anatomic TSA. The mechanism of such fixation failure is still unclear. The main goal of this study is evaluating in-vivo glenohumeral contact patterns in patients with osteoarthritic glenoids before and after TSA, to unravel the high rate of glenoid component loosening.

NCT ID: NCT06154421 Recruiting - Clinical trials for Rheumatoid Arthritis Metacarpophalangeal Joint

Metacarpophalangeal Joint Prostheses in Hand Surgery.

FLEX
Start date: January 4, 2024
Phase:
Study type: Observational

The primary working hypothesis of this study is whether KeriFlex® metacarpophalangeal joint prostheses provide an equivalent result to Swanson finger joint implants in patients with rheumatoid arthritis or post-traumatic osteoarthritis. Functional status will be measured by Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire no earlier than 1 year after surgery.

NCT ID: NCT06153381 Recruiting - Clinical trials for Shoulder Osteoarthritis

Virtual Rehabilitation Assistant Via Instant Messaging Communication to Promote Adherence to Rehabilitation After Reverse Shoulder Replacement

SIP_LaFe
Start date: September 1, 2023
Phase: N/A
Study type: Interventional

reverse shoulder replacement surgery is performed to improve the functionality and reduce pain of the affected shoulder. Now, it is necessary to carry out an appropriate rehabilitation process to optimize surgical results. The lack of health resources makes it essential for the patient to work autonomously once hospital rehabilitation is completed. But lack of adherence is one of the main barriers to recovery

NCT ID: NCT06152029 Recruiting - Osteoarthritis Clinical Trials

Temporary Peripheral Nerve Stimulation System for Osteoarthritis of the Knee

Start date: November 15, 2023
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to demonstrate the treatment outcomes of patients with chronic knee pain secondary to osteoarthritis that have received a temporary peripheral nerve stimulation system.

NCT ID: NCT06151834 Recruiting - Clinical trials for Osteoarthritis Thumb

Prospective Study of Arthrodesis of Finger Distal Interphalangeal Joints Using the Kerifuse Device

KF23
Start date: December 1, 2023
Phase: N/A
Study type: Interventional

Arthrodesis of a distal interphalangeal joint of the finger (DIP) is mainly performed for a degenerated and painful joint. Various stabilization methods have been used to provide compression at the arthrodesis site such as pins, steel wires, compression screws, headless compression screws, bioresorbable implants and intramedullary staples. Although with complications such as implant fractures or dorsal cortical erosion, intramedullary arthrodesis staples provide reliable pain relief and a consistent fusion rate while inevitably scarring the finger pulp or nail dystrophy. The aim of this study is to evaluate the bone fusion time during an arthrodesis performed with the Kerifuse shape memory implant.

NCT ID: NCT06150170 Recruiting - Knee Osteoarthritis Clinical Trials

Evaluation of the Efficiency of Propioceptive Study According to Radiological Stages in Patients With Knee Osteoarthritis

Start date: November 21, 2023
Phase: N/A
Study type: Interventional

Evaluation of the Efficiency of Propioceptive Study According to Radiological Stages in Patients with Knee Osteoarthritis

NCT ID: NCT06148779 Recruiting - Osteoarthritis Clinical Trials

Can Digitally Delivered First-line Osteoarthritis Treatment Improve Equal Access to Care

Access
Start date: January 1, 2022
Phase:
Study type: Observational

To improve chronically ill patients' health and quality of life, long-standing and continuous treatment is needed at an acceptable cost. The purpose of this study was to compare utilization of digital versus face-to-face delivered osteoarthritis (OA) treatment in the 21 different county councils of Sweden that are responsible for providing healthcare to the residents.