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Osteoarthritis clinical trials

View clinical trials related to Osteoarthritis.

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NCT ID: NCT03365271 Not yet recruiting - Knee Osteoarthritis Clinical Trials

The Post-operative Effect of Applying Drainage on Total Knee Arthroplasty

Start date: February 2018
Phase: N/A
Study type: Interventional

This multicenter clinical trial aims to investigate the exact effect of drainage use for osteoarthritis patients in total knee arthroplasty (TKA) on post-operative performance.

NCT ID: NCT03364790 Not yet recruiting - Clinical trials for Lumbar Osteoarthritis

Correlation Between the Lower Extremities and Lumbar Degenerative Diseases of the Elderly

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The study has before mentioned the concept of "knee - spine syndrome" domestically, on the basement of which, the new study intends to perform another further study on the relationship between lumbar and lower extremity degenerative diseases.

NCT ID: NCT03361449 Not yet recruiting - Osteoarthritis Clinical Trials

Effect of Flamingo Exercises on Balance

Start date: April 25, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to determine the effect of flamingo exercise on balance in patients with balance impairment due to senil osteoarthritis

NCT ID: NCT03358654 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Evaluating Safety and Efficacy of Mesenchymal Stem Cells From Umbilical Cord

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

This study was to evaluate the safety and efficacy of Mesenchymal Stem Cells (MSCs) from umbilical cord in the treatment of 7 knee OA patients by assessing unexplained local and systemic symptoms or death before and at 1, 2, 3, 6 months after the injection.

NCT ID: NCT03358641 Not yet recruiting - Clinical trials for Osteoarthritis, Knee

The Relationship Between Physical Activity and Radiographic Osteoarthritis Worsening

Start date: January 1, 2018
Phase: N/A
Study type: Observational

Wuchuan Osteoarthritis Study is a population-based longitudinal study of natural history of knee osteoarthritis and its risk factors. At baseline and follow-up visits, IPA-Q questionnaire and a radiographs at tibiofemoral (TF) joints will be taken in order to assess the relationship between physical activity and radiographic osteoarthritis worsening.

NCT ID: NCT03358381 Not yet recruiting - Clinical trials for Osteoarthritis, Knee

The Difference of Angle of Femoral Component Rotation in TKA With Gap Balance and Measured Resection Technique

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

Gap balance type and measured resection type total knee arthroplasty (TKA) have different influence on the rotation of femoral component.In this study, the rotation of patients received different type of TKA will be estimated and analysed through preoperation and postoperation knee joint CT scan.

NCT ID: NCT03357770 Not yet recruiting - Knee Osteoarthritis Clinical Trials

The Maximum Tolerated Dose of Mesenchymal Stem Cells From Umbilical Cord

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The aim of this study was to evaluate the maximum tolerated dose of Mesenchymal Stem Cells (MSCs) from umbilical cord in the treatment of human knee OA

NCT ID: NCT03357575 Not yet recruiting - Knee Osteoarthritis Clinical Trials

The Comparison of Efficacy and Safety of the Mesenchymal Stem Cells From Adipose and Hyaluronic Acid

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The aim of this study was to evaluate the efficacy and safety of Mesenchymal Stem Cells (MSCs) from adipose anticular injection in comparison with hyaluronic acid anticular injection in the treatment of human knee osteoarthritis(OA).

NCT ID: NCT03347500 Not yet recruiting - Osteoarthritis Clinical Trials

Microfluidic Organotypic Model for Monocyte Transendothelial Migration to the Joint in Obese Osteoarthritic Patients

MOTEM
Start date: December 2017
Phase: N/A
Study type: Observational

Osteoarthritis (OA) is the fastest growing cause of disability worldwide due to population ageing and increasing obesity incidence. Obese individuals have a higher risk of OA insurgence and severe progression due to several risk factors, including their systemic inflammation state and superior migratory ability of monocytes. In the present project we aim at the development of a novel 3D microfluidic organotypic model resembling the joint to investigate the migration ability of monocytes from obese and non-obese OA patients. We hypothesize that monocytes from obese OA patients display superior migration ability and a specific pattern of chemokine surface receptors compared to monocytes from non-obese OA patients. We also hypothesize that these features lead to a superior infiltration of monocytes/macrophages to the synovial membrane in obese OA patients. Based on this, our main aim will be to highlight differences between Mo from obese and non-obese OA patients in terms of surface receptors and migration ability in a microfluidic organotypic model.

NCT ID: NCT03327480 Not yet recruiting - Clinical trials for Osteoarthritis Thumb

The Effects of Two Different Orthosis on Pain, Hand Strength and Function in Patients With Thumb Carpometacarpal Osteoarthritis

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The investigators aimed to assess the effects of two different hand orthosis on hand functioning, pain, disability and quality of life in patients with thumb osteoarthritis