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Osteoarthritis clinical trials

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NCT ID: NCT02299271 Terminated - Clinical trials for Osteoarthritis of the Hip

Fascia Iliaca Block for Post-Operative Pain Control After Total Hip Arthroplasty

Start date: June 2014
Phase: Phase 4
Study type: Interventional

This study evaluates post-operative pain management and narcotic consumption in patients receiving a fascia iliaca block with local anesthetic versus patients receiving fascia iliaca block with saline for total hip arthroplasty.

NCT ID: NCT02290119 Terminated - Osteoarthritis Clinical Trials

Gait and Functional Improvement in Total Knee Arthroplasty With the Use of Verasense for Soft Tissue Balancing

Start date: April 1, 2018
Phase: N/A
Study type: Interventional

The primary objectives of this study are to understand the effects of soft-tissue balancing on Gait, function and rehabilitation potential after sensor-assisted Total Knee Arthroplasty and correlate Intra-operative subjective feel with OrthoSensor Outputs Secondary objectives are to quantify and observe: - Pain medication use - Swelling - Muscle strength and girth - Gait efficiency - Patient satisfaction - Activity levels, functional return (i.e., back to work, resume normal activities) - Patient perception of a balanced knee

NCT ID: NCT02254473 Terminated - Knee Osteoarthritis Clinical Trials

Evaluating the Efficacy of Lateral Heel Wedges of Osteoarthritis of the Knee

Start date: August 2014
Phase: N/A
Study type: Interventional

This study is looking at the efficacy of a sloped insole in patients with knee osteoarthritis. Regularly wearing a sloped insole over the course of one year will result in a wider joint space by x-ray in 60% of the subjects, a significant decrease in knee pain, decreased use of over the counter analgesics, and a clinically important improvement in the Womac pain and stiffness scale.

NCT ID: NCT02228538 Terminated - Clinical trials for Osteoarthritis of the Knee

Total Knee Arthroplasty Functional Outcomes Study Research Design

Start date: October 2013
Phase:
Study type: Observational

The purpose of this study is to obtain patient oriented and clinically oriented physical function outcomes both pre-operatively and post-operatively in patients receiving a total knee arthroplasty.

NCT ID: NCT02220478 Terminated - Clinical trials for Rheumatoid Arthritis

Signature Acetabular Posterior/Lateral Data Collection

Start date: November 2014
Phase: N/A
Study type: Interventional

The primary purpose of this pilot study is to evaluate the accuracy of cup placement between two instrumentation technologies: Cutting Guide and Conventional Instrumentation.

NCT ID: NCT02219581 Terminated - Postoperative Pain Clinical Trials

Steroids in Total Knee Arthroplasty

Start date: October 16, 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate if the use of two small doses of intravenous (IV) steroids around the time of knee replacement surgery decrease a patient's pain or use of pain medication. The investigators will also determine if the subjects receiving the steroid will have better pain control and better postoperative outcomes after their surgery.

NCT ID: NCT02196818 Terminated - Osteoarthritis Clinical Trials

A Multi-centre, Prospective Surveillance to Assess Mid-term Performance of the Mpact Cup

Start date: March 2013
Phase:
Study type: Observational

This is a multi-centre, prospective post marketing surveillance study to assess mid-term performance of the Mpact cup in subjects requiring primary total hip arthroplasty.

NCT ID: NCT02192190 Terminated - Clinical trials for Osteoarthritis, Knee

A Study of LY2951742 in Participants With Mild to Moderate Osteoarthritis Knee Pain

Start date: July 2014
Phase: Phase 2
Study type: Interventional

The main purpose of this study is to test if LY2951742 relieves mild to moderate knee pain. The study drugs will be given as an injection under the skin and as an oral capsule. The study will last about 28 weeks for each participant.

NCT ID: NCT02177162 Terminated - Clinical trials for Quality of Knee Osteoarthritis Care

Knee Osteoarthritis Care: A Quality Improvement Intervention in Physiotherapists

Start date: September 2014
Phase: N/A
Study type: Interventional

Physiotherapists' knee OA care is suboptimal. Exercise therapy including a combination of aerobic, muscle strengthening and functional exercises is not always performed and a lot of treatments are used for which there is no evidence. By a continuing education session and a pop-up in the electronic patient file, this study wants to improve knee OA care by focusing on combined exercise therapy. The study will be performed in collaboration with Pro-Q-Kine, an independent organization implementing quality improvement in Belgian physiotherapists' care. Besides Pro-Q-Kine the study will be performed in collaboration with two or three software producers of physiotherapists' electronic patient files that reached a national homologation for their respective software packages and covering a large part of the Flemish physiotherapists. Pro-Q-Kine will organize sessions of continuing education with a focus on optimal knee OA care. These sessions will be performed in LOK-groups (local peer-groups of physiotherapists who meet each other for continuing education). At these sessions the physiotherapists will be asked to take part to the study. A pop-up will be installed in the electronic patient file of the participating physiotherapists, lightening up when physiotherapists register a patient with knee OA. The pop-up includes a short message about optimal knee OA care. The physiotherapists will also receive a script for a query in their electronic patient files in order to extract those patients that initiated a treatment for knee OA between 1 year and 3 months before the therapists received education. These patients will receive a letter of their respective physiotherapists in which they are addressed to take part to the study. An informed consent, patient questionnaire and retour-envelope will be included. There will also be the opportunity to complete the questionnaire electronically with an electronic informed consent. The patient questionnaire will include some background details (such as age and gender) and details about the physiotherapeutic treatments they received for knee OA. The patient questionnaire will be coded with a number, referring to the physiotherapist and to the individual patient (the first patient of the first physiotherapist will be coded as 1.01, the 10th patient of the 14th physiotherapist will be coded as 14.10). Patients' names will not be revealed to the investigators and physiotherapists will not have any access to the completed patients' questionnaires. The general practitioners in the environment of the physiotherapist will (probably) receive a letter from the researchers. This letter will contain information about the importance of referral to a physiotherapist in knee OA care and about knee OA care in general. This letter will also refer to the study that is going on in physiotherapists' care, without details. Six months after the installation of the pop-up, the physiotherapists will be asked again to perform the query to extract patients out of the electronic patient file that have been treated for knee OA and whose treatment sessions had been started in the period of three months from the installation of the pop-up.

NCT ID: NCT02175576 Terminated - Clinical trials for Rheumatoid Arthritis

Randomized Controlled Clinical Outcomes of the Vanguard XP Bicruciate Knee System

GK9B
Start date: October 2014
Phase: N/A
Study type: Interventional

Randomized Controlled Study to determine if preservation of ligaments provides increased functional ability post-operatively in comparison to traditional TKA which sacrifices soft tissue.