Osteoarthritis of Knee Clinical Trial
Official title:
A Double-blind, Placebo-controlled, Randomized Study to Assess the Safety and Efficacy of 3VM1001 Cream for the Treatment of Chronic Pain Caused by Osteoarthritis of the Knee: A Proof of Concept Study
3VM1001 is a topical cream that may be useful for the treatment of chronic osteoarthritis of the knee. This proof of concept study is a randomized, placebo-controlled, double-blind study to compare treatment with 3VM1001 cream to an inactive cream placebo. Subjects will self-treat for 30 days.
3VM1001 is a topical cream that may be useful for the treatment of chronic osteoarthritis of the knee. This proof of concept study is a randomized, placebo-controlled, double-blind study to compare treatment with 3VM1001 cream to an inactive cream placebo. Subjects will self-treat for 30 days with investigational drug or placebo. Rescue medication with acetaminophen, up to 2g daily, is permitted. This study is intended to evaluate the safety and efficacy of 3VM1001 topical cream, a copper-containing cream. Subjects will self treat with drug or placebo three times daily for 30 days. All subjects will have a total of three visits to the clinic and will complete a daily diary each day for the 30 days of treatment. ;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT03274713 -
Efficacy of Electro-acupuncture Versus Manual Acupuncture on Knee Osteoarthritis
|
N/A | |
| Completed |
NCT04535596 -
Blood Flow Restriction Exercises and Conservative Exercises in Knee Osteoarthritis
|
N/A | |
| Completed |
NCT03918291 -
Whole-body Vibration Training on Functional Performance of the Elderly With Knee Osteoarthritis
|
N/A | |
| Recruiting |
NCT06263517 -
Clinical Trial to Assess Efficacy, Tolerability of Rising Doses of Clodronate in Painful Knee Osteoarthritis Patients
|
Phase 2/Phase 3 | |
| Completed |
NCT01453738 -
Allogeneic Mesenchymal Stem Cells in Osteoarthritis
|
Phase 2 | |
| Active, not recruiting |
NCT01027819 -
Comparison of Outcomes in Mobile and Fixed-bearing Total Knee Arthroplasty
|
Phase 4 | |
| Completed |
NCT01186211 -
Feasibility of Outpatient Total Knee Arthroplasty
|
||
| Active, not recruiting |
NCT00261066 -
Outcome Following Orthopaedic Surgery
|
||
| Completed |
NCT03484910 -
Biofeedback With Cycling Exercise in OA Knee Patients
|
N/A | |
| Recruiting |
NCT03884374 -
Pain Relief for OsteoArthritis Through Combined Treatment (PROACT)
|
N/A | |
| Completed |
NCT03492320 -
Progression of Health Related Quality of Life of Patients Waiting for Total Knee Arthroplasty
|
||
| Completed |
NCT01449552 -
Temporary Clamping of Drains Combined With Tranexamic Acid Reduce Blood Loss After TKA: A Prospective RCT
|
N/A | |
| Completed |
NCT06254976 -
Serum Nesfatin-1 and Human Cartilage Glycoprotein-39 Levels in Knee Osteoarthritis
|
N/A | |
| Completed |
NCT03428893 -
Mobile Technology to Support Physical Therapy Exercise
|
N/A | |
| Completed |
NCT05081921 -
Clinical Trial to Evaluate Safety and Efficacy of MesoCellA-Ortho Tissue-Engineered Advanced Therapy Product in Patients With Osteoarthrosis and Civilisation Diseases
|
Phase 1/Phase 2 | |
| Completed |
NCT02850068 -
Geniculate Artery Embolization for the Treatment of Knee Pain
|
N/A | |
| Active, not recruiting |
NCT03110172 -
Short-term Efficacy of Antidepressant in Patients Underwent TKA
|
Phase 1/Phase 2 | |
| Enrolling by invitation |
NCT02623660 -
Microcurrent Stimulation Reduces Post-Operative Swelling and Healing Time Following Knee Replacement Surgery
|
N/A | |
| Completed |
NCT02579174 -
Total Knee Replacement Component Alignment Using Manual Versus Custom Instrumentation
|
N/A | |
| Completed |
NCT00790985 -
Efficacy of Flavocoxid 500 mg Compared With Naproxen 500 mg in Subjects With Moderate-severe Osteoarthritis of the Knee
|
N/A |