Effects of Low Impact Elliptical Training on Knee Osteoarthritis Outcomes.

Osteoarthritis, Knee Clinical Trial

Official title:

Effects of Low Impact Elliptical Training on Knee Osteoarthritis Outcomes.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05977374
• Other study ID #: 01238
• Status: Completed
• Phase: N/A
• Start date: December 12, 2022
• Est. completion date: June 27, 2023

Study information

• Verified date: July 2023
• Source: Riphah International University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This research study is determined to see the effects of low-impact elliptical training on knee osteoarthritis outcomes.

Description:

This study is designed to reduce the load of knee osteoarthritis patients in society so that the individual lives a healthy life without getting caught in any form of disability. Knee osteoarthritis is a progressive and degenerative disease of a joint that includes focal cartilage loss, bony hypertrophy, synovial capsule thickening, and changes in structures of periarticular ligaments and peripheral muscles.

There are several techniques used to overcome the individual's pain, for instance, the mobilization of the joint, prolotherapy, and the use of different electrical modalities. meanwhile, an elliptical workout provides a positive result in reducing the progression of overall knee joint and cartilage defects. elliptical training is included in low-impact activities which are proven joint-friendly activities for the better improvement of the knee joint.

This activity works on a similar principle of cyclic compressive loading as occurs in the manual mobilization of the knee joint. This activity brings out the fluid from the synovial membrane on compression and upon decompression, the cartilage reabsorbs the oxygen and nutrients, which crosses the synovial barrier into the synovial fluid through a double diffusion system in the joint. The fluid then reaches the extra-cellular matrix that moves to the multiple layers of chondrocytes for the growth of the cartilage in OA.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 28
• Est. completion date: June 27, 2023
• Est. primary completion date: May 30, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 40 Years to 65 Years

Eligibility

Inclusion Criteria:

• 40- to 65-year-old.

• Diagnosed cases of Grade 1 and 2 Knee OA.

• Healthy and overweight patients will be included. (18.5- 29.5)

Exclusion Criteria:

• Acute musculoskeletal injury.

• Low back pain and Sciatica.

• Hip and ankle pathology.

• Acute infection, fever.

• The patient taking supplements and medications.

• Any knee deformity.

Related Conditions & MeSH terms

• Osteoarthritis
• Osteoarthritis, Knee

Intervention

Other:
• experimental and conventional group
Static stretchings of the lower limb, Ultrasound 1 MHz 1.5W/cm2 7 mins, knee isometrics, open chain activities, knee mobilizations grade 1 and 2, and home care plan.

Locations

Country	Name	City	State
Pakistan	Islamabad Physical Therapy & Rehabilitation Centre	Islamabad

Sponsors (2)

Lead Sponsor	Collaborator
Riphah International University	Health Education Research Foundation (HERF)

Country where clinical trial is conducted

Pakistan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Knee joint pain.	Pain is measured through KOOS questionnaire, which is the part of the KOOS and it has 9 items to identify pain scoring. A Likert scale is used and all items have five possible answer options scored from 0 (No problems) to 4 (Extreme problems) and each of the five scores is calculated as the sum of the items included.	Baseline, 6th week and 12th week.
Primary	Knee joint X-rays.	From the X-rays we will measure the medial and lateral knee joint space width through Radiant software.	Baseline, 6th week and 12th week.
Primary	Knee joint stiffness and symptoms.	This is the part of KOOS questinnaire, it involves 5 items of symptoms and 2 items of stiffnss to rule out knee joint symptoms and stiffness. A Likert scale is used and all items have five possible answer options scored from 0 (No problems) to 4 (Extreme problems) and each of the five scores is calculated as the sum of the items included.	Baseline, 6th week and 12th week.
Primary	Activities of daily livings impact on knee joint	This is also the part of KOOS questionnaire, it includes 17 items to find out the scoring. A Likert scale is used and all items have five possible answer options scored from 0 (No problems) to 4 (Extreme problems) and each of the five scores is calculated as the sum of the items included.	Baseline, 6th week and 12th week.
Primary	Sports activity impact on knee joint	We can find the sports scoring through KOOS questionnaire, it embroils 5 items. A Likert scale is used and all items have five possible answer options scored from 0 (No problems) to 4 (Extreme problems) and each of the five scores is calculated as the sum of the items included.	Baseline, 6th week and 12th week.
Primary	Quality of life impact on knee joint	This one is also the part of KOOS questionnaire. it contain 4 items for scoring. A Likert scale is used and all items have five possible answer options scored from 0 (No problems) to 4 (Extreme problems) and each of the five scores is calculated as the sum of the items included.	Baseline, 6th week and 12th week.