ZYNRELEF for Pain Management in Total Knee Arthroplasty

Status Recruiting

Clinical Trial Summary

The goal of this randomized controlled trial is to compare opioid medication consumption after surgery for patients who have a total knee replacement. The main questions it aims to answer are: - How well does the study drug control pain in the days after surgery? - Does the study drug reduce the amount of opioid analgesic consumed after surgery? Participants in the study group will undergo a total knee replacement as planned with their surgeon. In addition, be given the study drug, Zynrelef (combination of bupivacaine and meloxicam). Researchers will compare the above to a control group who will have a total knee replace only according to usual standards to see if there are any differences in the amount of a type of pain medication (opioid analgesic) consumed in the days following surgery.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05644496
Study type	Interventional
Source	Baptist Health South Florida
Contact	Yvette Hernandez
Phone	786-308-2217
Email	yvettesal@baptisthealth.net
Status	Recruiting
Phase	Phase 4
Start date	March 9, 2023
Completion date	April 2026

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