NSAID Treatment of Patients With Osteoarthritis

Osteoarthritis,Knee Clinical Trial

Official title:

BEVAR: Patientspecifik Behandling Ved Artrose - Et "Proof-of-concept"- Kvalitetssikringsstudie

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02967744
• Other study ID #: N-20140077
• Status: Completed
• Phase: N/A
• Start date: January 2016
• Est. completion date: February 1, 2018

Study information

• Verified date: February 2024
• Source: Aalborg University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The study investigates associations between pre treatment pain intensity and central pain mechanisms on the effect of 8-week treatment of NSAIDs in patients with knee osteoarthritis.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 162
• Est. completion date: February 1, 2018
• Est. primary completion date: January 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• Diagnosed Knee Ostoarthritis

Exclusion Criteria:

• Current ulcer diagnosed by endoscope

• Asthma or other allergic reaction to NSIADs

• Kidney disease

• Myocardial infarction within the last six months

• Severe hyper tension (systolic =180mmHg, diastolic =110mmHg)

• Severe thrombocytopenia (thrombocyst count <50x10^9/l)

• Insufficience lever or kidney function

Related Conditions & MeSH terms

• Osteoarthritis
• Osteoarthritis, Knee
• Osteoarthritis,Knee

Intervention

Drug:
• NSAID
NSAIDs are among the most common pain treatments for patients with osteoarthritis.

Locations

Country	Name	City	State
Denmark	Center for Sensory Motor Interaction, Aalborg University	Aalborg East

Sponsors (1)

Lead Sponsor	Collaborator
Aalborg University

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pain intensity measured on a 10cm visual analog scale	Patients will be asked to rate the pain intensity 8 weeks after treatment on a 10cm visual analog scale (0 indicating no pain, 10 indicating worst imaginable pain	8 weeks after treatment