Lundbeck TOMs Orthostatic Hypotension

Status Completed

Clinical Trial Summary

Orthostatic hypotension (OH), which consists in a significant reduction in blood pressure levels upon standing from a seated position, may affect approximately one in three patients with Parkinson's disease (PD). It usually presents as dizziness, lightheadedness, feeling faint, or feeling like you might black out while standing. This can significantly impact the quality of life (QoL) of PD patients, resulting in difficulties with balance, walking, and increased risk of falls. The main aim of this study is to evaluate whether the use of technological devices (a computerized system for analyzing abnormalities in walking in clinical settings and a wearable sensor to detect changes in postural unsteadiness in the home environment) may improve the detection of complications and the response to medical therapies for OH in patients with PD.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04510922
Study type	Interventional
Source	University of Cincinnati
Contact
Status	Completed
Phase	Phase 4
Start date	February 11, 2019
Completion date	December 31, 2020

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02705755` - TD-9855 Phase 2 in Neurogenic Orthostatic Hypotension (nOH)	Phase 2
Recruiting	`NCT05941819` - ARC Therapy to Restore Hemodynamic Stability and Trunk Control in People With Spinal Cord Injury	N/A
Completed	`NCT05529147` - The Effects of Medication Induced Blood Pressure Reduction on Cerebral Hemodynamics in Hypertensive Frail Elderly
Recruiting	`NCT02897063` - Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure	Phase 1
Completed	`NCT02726776` - Suspension Syndrome	N/A
Completed	`NCT01559675` - Trial Comparing Low Dose and High Dose Steroids in Patients Undergoing Colorectal Surgery	N/A
Not yet recruiting	`NCT04440085` - RaGuS Trial by Postoperative Patients	Phase 4
Recruiting	`NCT03732716` - Sarcopenia and Orthostatic Hypotension
Recruiting	`NCT05621460` - The Effect of Water Carbonation on Orthostatic Tolerance	N/A
Completed	`NCT02632318` - Dawn Simulation and Postural Hypotension	Phase 4
Completed	`NCT05729724` - Effect of Pharmacological Interventions on Systolic Blood Pressure Drops (SynABPM 2 Proof-of-concept)
Completed	`NCT03721393` - Data Collection - Of Syncope Tilt Table Testing Study
Completed	`NCT01030874` - Orthostatic Hypotension Treatment on Rehab Unit	N/A
Completed	`NCT01362751` - Orthostatic Hypotension in Elderly Nursing Home Residents	N/A
Completed	`NCT01223391` - Abdominal Compression in Orthostatic Hypotension	N/A
Completed	`NCT00248807` - A Study of Blood Pressure and Blood Supply to the Brain in Persons With a Spinal Cord Injury.	N/A
Terminated	`NCT00137319` - Impedance Threshold Device Tilt Study	N/A
Completed	`NCT05233865` - Hemodynamic Effects During Land vs Water Exercise for Older Adults With Orthostatic Hypotension	N/A
Suspended	`NCT01370512` - Droxidopa / Pyridostigmine in Orthostatic Hypotension	Phase 2
Recruiting	`NCT00452712` - Orthostatic Hypotension in Children With Acute Febrile Illness	Phase 2