Suspension Syndrome

Orthostatic Hypotension Clinical Trial

Official title: Suspension Syndrome

Status Completed

Clinical Trial Summary

Suspension syndrome refers to a potentially life-threatening condition that can occur in unconscious persons after prolonged suspension in a harness. To date, our understanding of the pathophysiology and appropriate treatment is based primarily on case reports and expert opinion. The main pathophysiological hypothesis implicates blood pooling in the lower extremity and lack of return via muscle pumping. However, a recent French study could not support this hypothesis. Other mechanisms, such as a central vagal reflex may play a role in the pathophysiology of suspension syndrome. The aim of this study is to better understand the pathophysiological basis of suspension syndrome and to develop practical recommendations for prevention and treatment.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Circulatory Collapse
• Circulatory Failure
• Hypotension
• Hypotension, Orthostatic
• Orthostatic Hypotension
• Shock
• Syncope, Vasovagal
• Syncope, Vasovagal, Neurally-Mediated

• NCT number: NCT02726776
• Study type: Interventional
• Source: Institute of Mountain Emergency Medicine
• Status: Completed
• Phase: N/A
• Start date: September 2015
• Completion date: December 2015