Critical Respiratory Events in Children Requiring Naloxone: Naloxone Use as Opioid Safety Measure

Opioid Induced Respiratory Depression Clinical Trial

Official title: Study of Hospital-wide Critical Respiratory Events Requiring Naloxone in a Pediatric Institution

Status Completed

Clinical Trial Summary

Opioids are the mainstay of analgesia in hospitalized children but opioid therapy is associated with life-threatening respiratory depression requiring antagonism with naloxone. Hence, it is hypothesized that naloxone requirement can be used as a quality measure of opioid safety. A retrospective medical chart review of 95 patients, who received naloxone for life threatening events, from June 2006-2012, is planned, to identify significant factors associated with risk for opioid induced respiratory depression and formulation of preventive strategies.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Opioid Induced Respiratory Depression
• Respiratory Insufficiency

• NCT number: NCT01860885
• Study type: Observational
• Source: Children's Hospital Medical Center, Cincinnati
• Status: Completed
• Phase: N/A
• Start date: August 2012
• Completion date: May 2013