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Oligohydramnios clinical trials

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NCT ID: NCT05559957 Completed - Clinical trials for Oligohydramnios, Delivered

Isolated Oligohydramnios Less Favorable Delivery and Neonatal Outcomes

Start date: January 1, 2020
Phase:
Study type: Observational [Patient Registry]

Oligohydramnios happens in 1-5% of term pregnancies. The clinical significance of isolated oligohydramnios been a matter of debate. We aimed in this study to investigate the impact of isolated oligohydramnios on the mode of delivery and risk of adverse perinatal outcome.

NCT ID: NCT05474326 Not yet recruiting - Oligohydramnios Clinical Trials

Effect of Intermittent Pneumatic Compression Device of Lower Limbs in Oligohydramnios

Start date: August 15, 2022
Phase: N/A
Study type: Interventional

the study will examine the effect of application of intermittent pneumatic pressure device on lower limbs on the amniotic fluid amount and fetal doppler indices in women with oligohydramnios

NCT ID: NCT05332015 Completed - Oligohydramnios Clinical Trials

The Effect of Oral Hypotonic Hydration in Isolated Oligohydramnios

Start date: April 28, 2022
Phase: N/A
Study type: Interventional

OBJECTIVE: The primary objective of our study is to compare the effects of routine hydration with additional 2 liters of normal water versus orally 2 liters of distilled water on the amount of amniotic fluid. HYPOTHESIS: İsolated oligohydramnios, secondary to depleted maternal intravascular volume, can be reversed better with orally hypotonic water.

NCT ID: NCT05059093 Completed - Clinical trials for Fetal Growth Restriction

Developing and Testing AI Models for Fetal Biometry and Amniotic Volume Assessment in Fetal Ultrasound Scans.

Start date: October 25, 2021
Phase:
Study type: Observational

Routine fetal ultrasound scan during the second trimester of the pregnancy is a low-cost, noninvasive screening modality that has been proven to lower fetal mortality by up to 20%. One of the critical elements of this exam is the measurement of fetal biometric parameters, which are the head circumference (HC), biparietal diameter (BPD), abdominal circumference (AC), and femur length (FL) measured on biometry standard planes. Those standard planes are taken according to quality standards first described by Salomon et al. and used as the guidelines of the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG). The biometric parameters extracted from them are essential to diagnose fetal growth restriction (FGR), the world's first cause of perinatal fetal mortality. Such measurements and image quality assessment are time-consuming tasks that are prone to inter and intraobserver variability depending on the level of skill of the sonographer or the physician performing the exam. Amniotic fluid (AF) volume assessment is also an essential step in routine screening scans allowing the diagnosis of oligo or hydramnios, both associated with increased fetal mortality rates. The AF is measured by two main "semi-quantitative" techniques: Amniotic Fluid Index (AFI) and the single deepest pocket (SDP). The latter is more specific as it lowers the overdiagnosis of oligo-amnios without any impact on mortality or morbidity and is easier to perform for the sonographer (only one measurement versus four in the case of the AFI technique). However, AF assessment remains a time-consuming and poorly reproducible task. Attempts to automate such biometric measurements and AF volume assessment have been made using Artificial Intelligence (AI) and deep learning (DL) tools. Studies showed excellent results "in silico," reaching up to 98 %, 95%, 93 % dice score coefficients for HC, AC, and FL measurements and 89 % DSC for AFI measurements. However, they were all conducted retrospectively without validation on prospectively acquired images. Reviews and experts have stressed the need for quality peer-reviewed prospective studies to assess AI tools' performance with real-world data. Their performance is expected to be worse and to reflect better their use in the clinical workflow. This study aims to develop DL models to automate HC, BPD, AC, and FL measurements and AF volume assessment from retrospectively acquired data and test their performances to those of clinicians and experts on prospective real-world fetal US scans.

NCT ID: NCT05043753 Not yet recruiting - Oligohydramnios Clinical Trials

"Fetal gRowth AbnorMality dEtection Trial"

FRAME
Start date: October 20, 2021
Phase: N/A
Study type: Interventional

The present trial intends to assess the diagnostic accuracy of symphysis fundal height (SFH) as opposed to SFH combined with point of care ultrasound to measure the fetal abdominal circumference (POC-US-AC) in identifying small and large for gestational age infants (SGA and LGA infants) among low-risk pregnant women cared for by midwives after 35 weeks' gestation. Low risk pregnancies will be evaluated at 35-38, 40, 41, and 41+ weeks' gestation by midwives trained in SFH measurement and POC-US. Formal obstetric US performed by a perinatologist (i.e high risk obstetrician) will be performed in case SFH and/or POC-US suspect fetal growth or amniotic fluid abnormalities. Prenatal evaluations will be compared to actual birthweights.

NCT ID: NCT04684680 Recruiting - Oligohydramnios Clinical Trials

The Role of Zamzam Water in Idiopathic Oligohydramnios

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the efficacy of drinking zamzam water versus tap water in increasing the AF index in women with oligohydramnios.

NCT ID: NCT04451109 Enrolling by invitation - Clinical trials for Gestational Diabetes

Dilapan-S®: A Multicenter US E-registry

Start date: December 1, 2020
Phase:
Study type: Observational

Objective of this registry is to collect a representative set of real world data on the use of Dilapan-S® for pre-induction cervical ripening in daily clinical practice. Upon completion of the registry, relevant collected data will be analyzed and published.

NCT ID: NCT03935607 Completed - Oligohydramnios Clinical Trials

The Added Contribution of Transvaginal Sonographic Evaluation of Amniotic Fluid Index

Start date: July 1, 2019
Phase:
Study type: Observational

The current study is based on the use of transvaginal sonography in the evaluation of oligohydramnios. Patients will be recruited after amniotic fluid index evaluation according to transabdominal sonography. After obtaining informed consent, transvaginal sonography will be used to evaluate and measure a possible amniotic fluid pocket that may precede the fetal presenting part.

NCT ID: NCT03815968 Not yet recruiting - Oligohydramnios Clinical Trials

Low Sodium Diet in Oligohydramnios Assigned for Conservative Management

Start date: February 2019
Phase: N/A
Study type: Interventional

The investigators want to examine whether low salt diet can increase the amniotic fluid index in patients diagnosed with oligohydramnios and assigned for conservative management. A randomized controlled trial

NCT ID: NCT03703037 Completed - Ultrasound Clinical Trials

Uterine, Fetal Cerebral Doppler and Oligohydramnios to Predict Abnormal Heart Rate Tracings in Postterm Pregnancies

Start date: January 1, 2016
Phase:
Study type: Observational

Objective: To estimate the value of uterine, fetal cerebral Doppler and oligohydramnios to predict abnormal fetal heart rate tracings in pregnancies at or beyond 41 weeks