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Old Age clinical trials

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NCT ID: NCT04142346 Completed - Old Age Clinical Trials

Breaking-up Sedentary Time and 2 Weeks Detraining

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

Regularly interrupting sedentary behavior (SB) with activity breaks may attenuate postprandial glucose (PPG) excursions and improve glycemic control. The investigators aimed to determine the effect of interrupting 7 hours of prolonged sitting with brief bouts of moderate physical activity (PA) (alternating between up/down stairs and sit/stand up from the chair) on postprandial glucose (PPG) responses in comparison with uninterrupted sitting. In addition, the investigators aimed to examine the effects of 2 weeks of detraining (DT) on PPG on both protocols. Non-diabetic, trained older adults (n = 15) will be recruited for a randomized crossover trial with two treatments performed in two different training conditions: 1) uninterrupted sitting protocol (CON); 2) seated with 2-minutes bouts of moderate PA every 30 minutes (INT). Both protocols will be performed in a trained condition and after 2 weeks of DT. In the early morning of each trial, participants will do an oral glucose tolerance test (OGTT) and 2 blood samples will be collected (fasting and after 2 hours); 2.5 hours after, participants will begin the protocol and two standardized meals will be provided (0 hours and at 3 hours). An iPro2 continuous glucose monitoring (CGM) system will record the average interstitial glucose concentration every 5 minutes. Positive incremental area under the curve (iAUC) and total area under the curve (pAUC) for glucose as well as mean glucose (MG) will be calculated using Matlab. Differences between both protocols and between the two different moments will be examined using generalized estimation equation (GEE), adjusting for sex and age (CI 95%).

NCT ID: NCT04103827 Withdrawn - Satisfaction Clinical Trials

Qoos Use Sustaining Health Among patIents hOspitalized in Geriatric mediciNe (QUSHION)

QUSHION
Start date: September 16, 2019
Phase:
Study type: Observational

Falls are a frequent and serious problem in old people. It is estimated that one-third of subjects over 65 years of age and 50% of those over 85 years of age have at least one fall per year (1). The traumatic and psychological consequences of falls contribute to the loss of functional independence and lead to early institutionalization (2). All activities of daily living require us to maintain a state of postural balance, whether standing, sitting, static or dynamic. Thus, good coordination is essential to maintain balance, reflecting both peripheral (muscular) and central (cognitive) motor control (3,4). Coordination skills between posture and movement decline during aging without associated disorder, and even more so when this aging is associated by cognitive disorders (5,6). On the contrary, as part of a balance rehabilitation program, an adapted training allows the partial recovery of the balance management process in elderly subjects who fall (7). Le Qoos® by LudHealth is technical foam equipment, which can be installed on the wall, to practice various physical exercises. It can therefore be used as a simple support, leaning on with hands, arms, feet or even the head, exerting contact points, pressures or even impacts with more or less force. Le Qoos® is an equipment that allows to perform, on the same object, gentle or tonic exercises, balance, flexibility, sheathing or muscle strengthening while having fun. We hypothesize that cognitive-physical stimulation workshops based on the use of the device Le Qoos® and is environment are i) adapted to geriatric fall prevention issues, ii) accessible to elderly hospitalized patients and health professionals, and iii) effective and safe to maintain and/or recover postural balance in elderly hospitalized patients. First step of this work is to assess whether "Le Qoos" is considered as usable par end-users of the device.

NCT ID: NCT04038983 Active, not recruiting - Old Age Clinical Trials

Risk for Short-term Adverse Events in Older Users in the Emergency Department

Start date: July 24, 2019
Phase:
Study type: Observational

The study evaluates the performance criteria of abnormal PRISMA-7 score, length of stay in Emergency department and in hospital, and hospital admission in older Emergency department users.

NCT ID: NCT03987347 Withdrawn - Cannabis Use Clinical Trials

Health Condition of Cannabis Consumers in the Canadian Population

Start date: December 1, 2020
Phase:
Study type: Observational

This study evaluates the health condition and its evolution with time of Cannabis consumers in the Canadian population.

NCT ID: NCT03978650 Active, not recruiting - Clinical trials for Neurocognitive Disorders

Risk Factors for Falls and Fall-related Injuries Associated With Mild Neurocognitive Disorders

Start date: July 23, 2019
Phase:
Study type: Observational

This study evaluates the risk for incident falls and fall-related injuries at the onset of neurocognitive disorders in older adults participating in the Canadian Longitudinal Study

NCT ID: NCT03978182 Withdrawn - Depression Clinical Trials

Accelerated Deep TMS in the Elderly Depressed: A Brain Imaging Approach

Start date: June 2019
Phase: N/A
Study type: Interventional

With a growing number of elderly persons, geriatric depression - associated with important morbidity and mortality- is becoming a significant health problem. Given the risk of polypharmacy and increased side effects, alternative non pharmaceutical treatments such as repetitive transcranial magnetic stimulation (rTMS) may be a solution. Given recent positive results with accelerated rTMS in the elderly depressed, it is of interrest to continue to develop promising non-invasive treatment stimulations. The FDA approved deep brain TMS (dTMS) technique may be a promising option, targeting the brain underneath the neocortex with potentially better response and remission rates. Therefore, in a sham-controlled cross-over fashion, the investigators will treat 44 geriatric depressed patients with accelerated dTMS (5 sessions/day over 4 days only), and evaluate clinical efficacy and safety. Because new introduced rTMS paradigms should be rigorously neurobiologically examined before applying them on a regular basis, this research will include multimodal brain imaging techniques to elucidate the working mechanisms of this application in order to optimize treatment for such populations.

NCT ID: NCT03962985 Active, not recruiting - Social Isolation Clinical Trials

Effects of Montreal Museum of Fine Arts Visits and Older Community Dwellers With a Precarious State

Start date: July 23, 2019
Phase: N/A
Study type: Interventional

This study evaluates the effects of MMFA visits on psychological, health, social conditions and personal interactions in older community dwellers with a precarious state and to determine whether these effects may change precarity.

NCT ID: NCT03704441 Completed - Old Age Clinical Trials

ED50 and ED95 of Intrathecal Hyperbaric Bupivacaine With Fentanyl for Transurethral Prostatectomy in Elderly Patients

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

As people age, the incidence of prostate hyperplasia increases. So patients under Transurethral Resection of Prostate(TURP) or Holmium Laser Ennucleation of Prostate(HoLEP) are mostly ole age people. Most old age patient has several underlying disease. So patients can develop high mortality and morbidity. Most surgeries for Prostate Resection are taken under Spinal anesthesia. Adequate block level for Prostate Resection is T10. But sometimes, old age patients can develop severe complication after spinal anesthesia. So we started this study to know the adequate drug concentration for Spinal anesthesia taken for Prostate Resection surgery.

NCT ID: NCT03656887 Completed - Diabetes Clinical Trials

Screening for Hypoglycemia in an Institutionalized Elderly Diabetic Population.

HAGED
Start date: January 8, 2019
Phase:
Study type: Observational

Diabetes is a major public health problem that has been growing steadily in recent years. Its prevalence is very high in the elderly, in whom there is an increased risk of hypoglycemia. Hypoglycaemia in elderly diabetics has serious consequences: - increased mortality, - increased cardiovascular morbidity, - increased risk of falling, - impairment of quality of life. - Hypoglycaemia is also a risk factor for dementia in type 2 diabetes. The frequency of asymptomatic and atypical hypoglycemia has been shown to be greater in the elderly, but the exact prevalence of hypoglycemia in the elderly remains unknown. Elderly diabetic patients in institutions are particularly fragile and have more frequent cognitive problems than non-diabetic subjects. A study conducted in this population of patients showed that a third of them had HbA1C <6.5%, which suggests a higher frequency of hypoglycemia though the figures were not available. We therefore decided to conduct a study to assess the frequency of hypoglycemia in order to better understand the contributing factors and to improve the management of this fragile population.

NCT ID: NCT03549585 Completed - Old Age Clinical Trials

End-of-Life Patient Identification Assistance in Acute GEriatric Medicine

ARPEGE
Start date: June 27, 2017
Phase:
Study type: Observational

The main objective of this project is to build a tool, adapted to the French geriatric population, that will predict the risk of death at three months after hospitalization in acute geriatric medicine. This tool will be built using selected items via a review of the literature published in 2015. The 8 items of the CriSTAL tool will be collected prospectively in all patients hospitalized successively in the 2 post-emergency geriatric services (PUG) of the University Hospital of Toulouse, over a period of 9 months, by a dedicated clinical research associate. Patient survival will be assessed by obtaining the vital status of the cohort via CépiDC