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Ocular Hypertension clinical trials

View clinical trials related to Ocular Hypertension.

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NCT ID: NCT01664039 Completed - Glaucoma Clinical Trials

An Efficacy and Tolerability Study of TRAVATAN® Versus LUMIGAN®

Start date: September 2012
Phase: Phase 4
Study type: Interventional

The purpose of this study is evaluate effects of TRAVATAN® versus LUMIGAN® on intraocular pressure (IOP) and ocular surface and inflammatory biomarkers.

NCT ID: NCT01658839 Completed - Glaucoma Clinical Trials

Pharmacokinetic and Safety Study of Travoprost 0.004% in Pediatric Glaucoma Patients

Start date: January 2013
Phase: Phase 1
Study type: Interventional

The purpose of this study was to assess the safety and describe the steady-state plasma pharmacokinetic (PK) profiles of Travoprost ophthalmic solution, 0.004% (new formulation) following a once daily administration for 7 days in pediatric glaucoma or ocular hypertension patients.

NCT ID: NCT01655758 Completed - Ocular Hypertension Clinical Trials

24-hour Control of Intraocular Pressure (IOP) in Ocular Hypertension

Start date: January 2002
Phase: Phase 4
Study type: Interventional

This study was designed to compare the 24-hour efficacy on intra ocular pressure (IOP) of drugs acting either on aqueous humor production ("inflow drugs") or on aqueous humor outflow ("outflow drugs") in human eyes affected by ocular hypertension and virgin to treatment. The enrolled patients will be exposed, in a cross-over design, to n = 2 aqueous suppressants and n= 3 uveoscleral outflow enhancers, and 24 hr IOP will be measured. It is hypothesised that outflow drugs may offer a better and more stable control of IOP through the 24 hours.

NCT ID: NCT01654484 Completed - Clinical trials for Glaucoma and Ocular Hypertension

A Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Patients With POAG or OHT

Start date: July 2012
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to investigate the safety and efficacy of up to three concentrations of DE-117 ophthalmic solution (Low Dose, Medium Dose, and High Dose) as monotherapy and as adjunctive therapy (DE-117 ophthalmic solution with 0.0015% tafluprost) in subjects with primary open-angle glaucoma or ocular hypertension.

NCT ID: NCT01652664 Completed - Pediatric Glaucoma Clinical Trials

Study of Travoprost Ophthalmic Solution, 0.004% Compared to Timolol (0.5% or 0.25%) in Pediatric Glaucoma Patients

Start date: September 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the intraocular pressure (IOP)-lowering efficacy of Travoprost 0.004% POLYQUAD (PQ) ophthalmic solution compared to Timolol ophthalmic solution (0.5% or 0.25%) in pediatric glaucoma patients.

NCT ID: NCT01646151 Completed - Ocular Hypertension Clinical Trials

A Study Comparing IOP-Lowering Treatments to Bimatoprost in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Start date: May 2012
Phase: N/A
Study type: Observational

An observational study comparing changing from an IOP-lowering treatment to a bimatoprost-containing IOP treatment in primary open-angle glaucoma (POAG) or ocular hypertension (OHT). Visits and treatment are per normal clinical practice.

NCT ID: NCT01637246 Completed - Ocular Hypertension Clinical Trials

A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Were Insufficiently Responsive to Monotherapy

Start date: April 2009
Phase: N/A
Study type: Observational

This is a retrospective chart review and will assess changes in IOP after treatment with any fixed combination in patients who previously received monotherapy.

NCT ID: NCT01632423 Completed - Ocular Hypertension Clinical Trials

A Study of Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)

Start date: February 2010
Phase: N/A
Study type: Observational

This is an observational study of Lumigan® 0.01% (bimatoprost) treatment in clinical practice for patients with Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT).

NCT ID: NCT01628614 Completed - Ocular Hypertension Clinical Trials

A Study of Intraocular Pressure (IOP) Reduction in Newly Diagnosed Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)

Start date: November 2010
Phase: N/A
Study type: Observational

This is an observational study and will evaluate IOP reduction in newly diagnosed patients with POAG or OHT. All care (including treatment and diagnostic procedures) provided is at the discretion of the participating physicians according to their clinical judgment and the local standard of medical care.

NCT ID: NCT01628601 Completed - Ocular Hypertension Clinical Trials

GANfort® in Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Are Insufficiently Responsive to Monotherapy

Start date: May 2010
Phase: N/A
Study type: Observational

This is an observational study of patients diagnosed with Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT) who are insufficiently responsive to monotherapy and who are prescribed GANfort® (fixed combination of 0.3 mg bimatoprost and 5 mg timolol) by their physician.