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Ocular Hypertension clinical trials

View clinical trials related to Ocular Hypertension.

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NCT ID: NCT02537015 Completed - Ocular Hypertension Clinical Trials

An Open-label Extension Study to Evaluate the Safety of the 13 mg Bimatoprost Ocular Insert

OLE2
Start date: August 10, 2015
Phase: Phase 2
Study type: Interventional

This study evaluated the long-term (9-months) safety of the Bimatoprost Ocular Insert in participants with Glaucoma or Ocular Hypertension who completed study FSV5-004. All the participants received Bimatoprost Ocular Insert and wore it for approximately 3 months (12 weeks), then had that Insert removed and a new Insert placed for another 26 weeks (approximately 6 months).

NCT ID: NCT02531152 Completed - Clinical trials for Open Angle Glaucoma -Ocular Hypertension

28-Day Repeated Topical Study to Evaluate the Safety and Activity of 5 Escalating Dose Levels of SAR366234 and One Dose of Latanoprost in Patients With Open Angle Glaucoma or Ocular Hypertension

Start date: September 2015
Phase: Phase 1
Study type: Interventional

Primary Objective: To assess the local and systemic safety and tolerability of ascending repeated topical doses of SAR366234 monotherapy in patients with open angle glaucoma (OAG) or ocular hypertension (OHT) as compared to latanoprost. Secondary Objective: To assess the pharmacodynamic activity of ascending repeated topical doses of SAR366234 in patients with OAG or OHT as compared to latanoprost.

NCT ID: NCT02512042 Completed - Glaucoma Clinical Trials

Bioequivalence Study With Clinical Endpoint Comparing Brinzolamide 1% Ophthalmic Suspension to Azopt® 1% Ophthalmic Suspension In the Treatment of Chronic Open Angle Glaucoma or Ocular Hypertension in Both Eyes

Start date: April 2015
Phase: Phase 3
Study type: Interventional

This is a randomized, double blind, two-arm, parallel group, active controlled bioequivalence study, at multiple clinical trial sites designed to demonstrate bioequivalence of Brinzolamide 1% ophthalmic suspension (manufactured by Indoco Remedies Ltd. for Watson Pharma Pvt Ltd.), to Brinzolamide (Azopt®) 1% ophthalmic suspension of Alcon Laboratories, Inc. in the treatment of chronic open angle glaucoma or ocular hypertension in both eyes.

NCT ID: NCT02507687 Completed - Ocular Hypertension Clinical Trials

Comparison of Bimatoprost Sustained Release (SR) to Selective Laser Trabeculoplasty (SLT) in Adults With Open-Angle Glaucoma or Ocular Hypertension

Start date: August 27, 2015
Phase: Phase 3
Study type: Interventional

This study will evaluate the intraocular pressure (IOP)-lowering effect and safety of bimatoprost SR compared with selective laser trabeculoplasty in patients with open-angle glaucoma or ocular hypertension who are not adequately managed with topical IOP-lowering medication for reasons other than medication efficacy (e.g., due to intolerance or nonadherence).

NCT ID: NCT02466399 Completed - Glaucoma Clinical Trials

POLAT-001 Compared to Latanoprost Ophthalmic Solution in Patients With Ocular Hypertension and Open-angle Glaucoma

Start date: July 2015
Phase: Phase 2
Study type: Interventional

This is an open-label, randomized, multi-center, active-controlled parallel-comparison of POLAT-001 to latanoprost ophthalmic solution in patients with ocular hypertension and primary open-angle glaucoma.

NCT ID: NCT02434250 Completed - Cataract Clinical Trials

Selective Laser Trabeculoplasty After Failed Phacoemulsification With Eximer Laser Trabeculectomy

SLT
Start date: May 2015
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the efficacy of selective laser trabeculoplasty after a prior failed phacoemulsification and Eximer Laser Trabeculectomy.

NCT ID: NCT02419508 Completed - Ocular Hypertension Clinical Trials

SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA)

Start date: August 7, 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the additive intraocular pressure (IOP) lowering effect of brinzolamide 1%/brimonidine 0.2% (dosed twice per day (BID)) when added to a prostaglandin analogue (PGA) in subjects with open-angle glaucoma or ocular hypertension.

NCT ID: NCT02390245 Completed - Cataract Clinical Trials

Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study

Start date: September 2014
Phase: N/A
Study type: Interventional

The goal is to conduct a 5-year prospective, randomized controlled trial to test an innovative, community-based intervention using posterior and anterior fundus photography of the optic nerve and macula and intraocular eye pressure measurements to improve access and utilization of eye care to detect, treat, and manage high-risk patients with previously undiagnosed glaucoma and other eye diseases. Research shows that subject failure to attend follow-up eye care appointments diminishes any previous benefits of community screenings for glaucoma. Greater adherence to follow-up visits can reduce glaucomatous blindness.

NCT ID: NCT02384772 Completed - Glaucoma Clinical Trials

Survey of Patients Taking IOP-Lowering Eye Drops

Start date: January 2015
Phase: N/A
Study type: Observational

Survey to assess perspectives of patients prescribed IOP-lowering eye drops at a single office visit.

NCT ID: NCT02371746 Completed - Clinical trials for Glaucoma and Ocular Hypertension

Safety and Efficacy of ENV515 Travoprost Extended Release (XR) in Patients With Bilateral Ocular Hypertension or Primary Open Angle Glaucoma

Start date: January 1, 2015
Phase: Phase 2
Study type: Interventional

This is a multiple cohort study that will evaluate the safety and efficacy of ENV515 travoprost XR in patients with open-angle glaucoma or ocular hypertension.