Systemic Steroids Plus Antibiotics in Sleep Apnea Syndrome in Children

Status Terminated

Clinical Trial Summary

The purpose of this study is to investigate the effect of treatment with a steroid and antibiotic on the size of the tonsils and symptoms of children with OSAS.

Clinical Trial Description

We will enroll children between 18 months and 12 years of age with mild sleep apnea and treat them with 5 days of prednisolone and 10 days of amoxicillin/clavulanate. We will obtain a questionnaire pre and post treatment and ask the parents to tell us if they think the child has improved enough after treatment to forego surgery. If not, they will undergo an adenotonsillectomy to relieve their sleep apnea and if yes, we will repeat the sleep study to make sure that the apnea has resolved. ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00456339
Study type	Interventional
Source	University of Chicago
Contact
Status	Terminated
Phase	Phase 4
Start date	July 2006
Completion date	July 2007

View Details

See also
Status	Clinical Trial	Phase
Withdrawn	`NCT05164211` - Didgeridoo Treatment to Improve Pharyngeal Compliance in Obstructive Sleep Apnea-hypopnea Syndrome in Children	N/A
Active, not recruiting	`NCT05049928` - m-Rehab OSA : Impact of a Telerehabilitation Program Associated With CPAP on Severity Markers of Obstructive Sleep Apnea Syndrome	N/A
Not yet recruiting	`NCT04538274` - Trained Patient Involvement to Promote the Resumption of CPAP in Patients Who Have Discontinued Its Use	N/A
Completed	`NCT02967367` - Reliability of Consumer Sleep Trackers in Patients Suffering From Obstructive Sleep Apnea Syndrome	N/A
Completed	`NCT02180672` - Steroids for Pediatric Apnea Research in Kids	Phase 3
Recruiting	`NCT01561677` - Consequences of Obstructive Sleep Apnea Syndrome (OSAS) After Ischemic Subtentorial Stroke.	N/A
Completed	`NCT01808508` - Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome	N/A
Completed	`NCT01193738` - Osteopathy and Obstructive Sleep Apnea Syndrome	N/A
Completed	`NCT01090297` - Continuous Positive Airway Pressure (CPAP) Mode Impact on Clinical Blood Arterial Pressure	N/A
Completed	`NCT00801671` - Russian Study of the Effect of Continuous Positive Airway Pressure (CPAP) in Hypertension	Phase 3
Completed	`NCT00850876` - Heated Humidified Continuous Positive Airway Pressure and Nasal Physiology	N/A
Completed	`NCT02085720` - Prevalence of OSAS in Chinese Elderly and Its CPAP Compliance	N/A
Recruiting	`NCT00874913` - Study of Ocular Blood Flow in Patients With Glaucoma and/or Obstructive Sleep Apnea Syndrome (OSAS)	N/A
Completed	`NCT00156442` - A Study to Examine the Relationship Between Sleep Apnea and Cleft Lip/Palate	N/A
Completed	`NCT00222963` - Pilot Study to Assess the Effectiveness of Tonsil and Adenoidectomy (T+A) in Overweight Children and Adolescents	N/A
Withdrawn	`NCT00156455` - Sleep Disordered Breathing in Children With Single Ventricle Physiology	N/A
Completed	`NCT01045499` - LAGB as a Treatment for Morbid Obesity in Adolescents	N/A
Completed	`NCT02995837` - Cerebral Blood Flow and Childhood Obstructive Sleep Apnea
Withdrawn	`NCT02559427` - SPA Therapy in the Treatment of Sleep Apnea Syndrome	N/A
Completed	`NCT02522819` - Feasibility Evaluation of CPAP in the Treatment of Obstructive Sleep Apnea Synchrone in the Acute Phase of Stroke	N/A