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Obstetric Labor Complications clinical trials

View clinical trials related to Obstetric Labor Complications.

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NCT ID: NCT03922087 Completed - Obesity Clinical Trials

No-worry Baby Project

Start date: November 20, 2018
Phase:
Study type: Observational

The Huizhou mother-infant cohort was set up to investigate the effect of dietary factors and environmental exposures during pregnancy on health consequences of mothers and offsprings in Huizhou, China.

NCT ID: NCT03862820 Not yet recruiting - Clinical trials for Obstetric Labor Complications

Dynamic Ultrasound for Prediction of Adhesion Section

Start date: April 2019
Phase:
Study type: Observational

1. To validate the use of dynamic ultrasound for prediction of adhesions in women undergoing repeated cesarean section. 2. To detect the interobserver and intraobserver reliability of this method

NCT ID: NCT03830879 Recruiting - Clinical trials for Gestational Diabetes

Shenzhen Birth Cohort Study

Start date: March 6, 2018
Phase:
Study type: Observational

The Shenzhen Birth Cohort Study was set up to investigate the effect of early life environmental exposures on short- and long-term health consequences in Shenzhen, China.

NCT ID: NCT03757598 Completed - Newborn Morbidity Clinical Trials

ePartogram Effectiveness Study in Kenya

Start date: August 1, 2016
Phase: N/A
Study type: Interventional

Quasi-experimental study to evaluate whether clinical care offered to clients was more appropriate and in line with WHO recommendations for care in normally progressing labor and in labor with complications, among providers using the novel intervention, ePartogram (an electronic version of the WHO paper partograph) vs. providers who offered care using the standard paper partograph, and whether fetal/newborn outcomes were improved among cases where partograph was used.

NCT ID: NCT03752879 Completed - Labor Complication Clinical Trials

The Association Between Kristeller Maneuver and Pelvic Floor Trauma After Vaginal Delivery

Start date: May 18, 2019
Phase:
Study type: Observational

We want to investigate the association between fundal pressure in the second stage and the risk of levator ani muscle (LAM) injury.

NCT ID: NCT03719625 Not yet recruiting - Cesarean Clinical Trials

Norepinephrine Versus Ephedrin for Prevention of Post Spinal Anesthesia in Cesarean Section

Start date: January 2, 2019
Phase: Phase 4
Study type: Interventional

Spinal anesthesia is still the gold standard anesthetic method for elective and urgent cesarean section, the post spinal hypotension remains the most frequent complication of this procedure and is still responsible of considerable maternel and fetal morbidity. It is recommanded to prevent this post spinal hypotension with fluid coloading and prophylactic vasopressors administration. The aim of this study is to compare the efficency and the safety of norepinephrin and ephedrin prophylactic administration to reduce the incidence of post spinal hypotension in cesarean section.

NCT ID: NCT03592160 Completed - Clinical trials for Pelvic Floor Disorders

Role of Rehabilitation for the Repair of Pelvic Floor Injuries Associated to Vaginal Delivery Identified by 3/4D Transperineal Ultrasound

Start date: January 1, 2016
Phase: N/A
Study type: Interventional

SUMMARY: (Objective, design, scope of the study, subjects of study, instrumentation, results, conclusions) Objectives: To evaluate if the physiotherapy treatment in pelvic floor dysfunctions, identified by transperineal ultrasound 3 / 4D, in postpartum improve the tone and functionality of pelvic floor. Design: Post-authorization, prospective, longitudinal randomized intervention study Scope: Full-term deliveries at the University Hospital. Subjects of study: Full-term primiparous and full-term pregnancies with pelvic floor lesion, identified by transperineal ultrasound 3 / 4D, which are randomized between the physiotherapy treatment of pelvic floor and the non-work. Variables: Primary variable: Assess the improvement in contractility / tone, evaluation by manometry and assess the anatomical improvement of the area of ?? the genital hiatus, stay by transperineal ultrasound 3 / 4D. Secondary variables: Identify the levator ani muscle injury rate, estimate the sonographic changes in the levator ani muscle through rehabilitation. Analyze the improvement of the symptoms associated with the public organic prolapse and evaluate the improvement of the quality of life. Data analysis: To detect a difference of 10% in the reduction of the size of the index between the study groups (not intervened / intervened) after 6 months of intervention, standard deviation 10%, Error-alpha 5%, Error- beta 10% (P90%) we need 23 women in each group. Assuming a loss of 10% in the follow-up, the final size would be 52 women, 26 per group.

NCT ID: NCT03547791 Recruiting - Clinical trials for Twin Pregnancy, Antepartum Condition or Complication

Effects of ACS in Twin With LPB: Study Protocol for a RCT

Start date: May 5, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

This study will be the first study that evaluates the effectiveness of antenatal corticosteroid (ACS) in late preterm twin neonates.

NCT ID: NCT03523780 Completed - Clinical trials for Obstetric Labor Complications

Transfusion of Whole Blood and Cesarean Delivery: A Retrospective Review

Start date: August 10, 2017
Phase:
Study type: Observational

The rate of postpartum hemorrhage (PPH) has risen dramatically in the developed world, along with a rise in blood transfusion rates. The rate of cesarean delivery has increased dramatically in the past decade and is well over 30% in the United States. With an increase in primary and repeat cesarean delivery, comes the added risk of abnormal placentation, which can contribute to maternal and fetal morbidity and mortality via placenta accreta, increta, and percreta. The incidence of accreta has increased 10-fold over the past 50 years, becoming the most common reason for cesarean hysterectomy in highly industrialized countries. These conditions have tremendous impact on maternal outcomes. Although whole blood (WB) contains all of the individual blood components, there are concerns for the use of WB due to the potential limitations such as the hemostatic efficacy of platelet after cold storage, the risk of hemolytic transfusion reaction following the transfusion of un-cross matched WB and the logistical issues in providing WB. Traditional obstetric transfusion protocols involve blood component therapy. Whole blood contains all components and could be more efficient for massive transfusion in obstetric hemorrhage. Trauma resuscitation protocols mimic whole blood in the 1:1:1 transfusion protocols of packed red blood cells to plasma to platelet ratio. It is difficult to compare trauma resuscitation to obstetric hemorrhage, but both can involve significant resuscitation and serious sequelae from unnecessary transfusion. The use of WB instead of component therapy may reduce the multiple organ dysfunction rates due to the rapid resolution of shock and coagulopathy. Additionally, the number of donor exposure is important factor for the transfusion-related allergic reactions including severe systemic reactions such as anaphylaxis. Use of WB may decrease number of donor exposure. The secondary aim is to compare the incidence of 3 common adverse outcomes associated with the transfusion of blood products in subjects who receive whole blood versus component therapy. Investigators hypothesize that the patients receiving WB will have fewer incidences of a) acute renal failure, b) acute heart failure and c) transfusion-related lung disease compared to those receiving component therapy.

NCT ID: NCT03471858 Recruiting - Pregnancy Related Clinical Trials

Mechanical Dilation of the Cervix in a Scarred Uterus

MEDICS
Start date: February 14, 2019
Phase: N/A
Study type: Interventional

To determine if mechanical labour induction can offer a safer and effective alternative to prostaglandins to women with previous caesarean section attempting trial of labour after caesarean (TOLAC).