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Effect of Protein Source During Ketogenic Weight Loss Intervention

Obesity Clinical Trial

Official title:
Effect of Protein Source During Ketogenic Weight Loss Intervention on Lipid Metabolism and Inflammation

Clinical Trial Summary

This randomized, controlled, single-blinded study will investigate how the protein source in a high-protein ketogenic diet affects metabolic weight loss outcomes after a 12-week dietary intervention

Clinical Trial Description

This randomized, controlled, single-blinded study will compare how a ketogenic weight loss diet, supplemented with either animal- or plant-based protein affects: (i) metabolic markers (adipokine and cytokine) in adipose tissue and blood, (ii) adipose tissue immune cell profiles, and (iii) adipocyte characteristics and their interaction with other cells (e.g. immune cells and muscle cells). To better determine how tissue characteristics affect the whole body level, the relationships between adipose tissue characteristics and blood lipid and inflammatory markers will also be examined. Participants undergo anthropometric measurements, questionnaires, body composition assessment, energy assessment, blood draws, and adipose tissue biopsies from the abdominal and femoral adipose tissue depots ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06461806
Study type Interventional
Source Concordia University, Montreal
Contact
Status Active, not recruiting
Phase N/A
Start date October 1, 2022
Completion date December 2024
View Details
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