Postoperative BMI Changes and Functional Outcomes in Knee and Hip Arthroplasty

Obesity Clinical Trial

Official title:

The Effect of Changes in Body Mass Index After Total Knee and Hip Arthroplasty on Patient Functional Scores

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06440863
• Other study ID #: Y7MQG7gO
• Status: Completed
• Phase: N/A
• Start date: January 1, 2018
• Est. completion date: May 1, 2024

Study information

• Verified date: June 2024
• Source: Istanbul University - Cerrahpasa (IUC)
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

PURPOSE Obesity poses challenges to preoperative mobility and functional recovery for arthroplasty patients, yet postoperative weight loss remains elusive. This study aims to investigate postoperative weight changes and their impact on functional scores following knee and hip arthroplasty, exploring factors influencing these changes.

METHODS A total of 459 knee and hip arthroplasty cases with a 2-year follow-up were analyzed. BMI and Oxford scores were tracked, alongside factors including comorbidities, corticosteroid use, physiotherapy, and unilateral vs. bilateral surgery.

EXPECTED OUTCOMES Based on the study's design and the data available, we anticipate observing the impact of changes in patients' BMI on clinical scores as an independent variable. Additionally, we aim to elucidate the effects of comorbidities, corticosteroid use, physiatrist follow-up, and the type of surgical procedure on both BMI and clinical outcomes. Through this analysis, we expect to gain a comprehensive understanding of how these factors interplay to influence postoperative recovery and overall patient health.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 459
• Est. completion date: May 1, 2024
• Est. primary completion date: December 30, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 80 Years

Eligibility

Inclusion Criteria:

• Patients who underwent primary TKA and THA with a 2-year follow-up were included

Exclusion Criteria:

• Patients who underwent bariatric surgery before or after the surgery

• Incomplete 2-year follow-up

• Whom BMI or Oxford scores could not be accessed

Related Conditions & MeSH terms

• Arthropathy
• Joint Diseases
• Obesity

Intervention

Procedure:
• Total Knee Arthroplasty
Patients undergoing total knee arthroplasty
• Total Hip arthroplasty
Patients undergoing total hip arthroplasty

Locations

Country	Name	City	State
Turkey	Istanbul University - Cerrahpasa, Cerrahpasa Faculty of Medicine	Istanbul	Fatih

Sponsors (1)

Lead Sponsor	Collaborator
Istanbul University - Cerrahpasa (IUC)

Country where clinical trial is conducted

Turkey, 

References & Publications (3)

Inacio MC, Silverstein DK, Raman R, Macera CA, Nichols JF, Shaffer RA, Fithian D. Weight patterns before and after total joint arthroplasty and characteristics associated with weight change. Perm J. 2014 Winter;18(1):25-31. doi: 10.7812/TPP/13-082. — View Citation

Riddle DL, Singh JA, Harmsen WS, Schleck CD, Lewallen DG. Clinically important body weight gain following knee arthroplasty: a five-year comparative cohort study. Arthritis Care Res (Hoboken). 2013 May;65(5):669-77. doi: 10.1002/acr.21880. — View Citation

Woodruff MJ, Stone MH. Comparison of weight changes after total hip or knee arthroplasty. J Arthroplasty. 2001 Jan;16(1):22-4. doi: 10.1054/arth.2001.9826. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	BMI	Body Mass Index (BMI) is a person's weight in kilograms divided by the square of height in meters.	2 years
Primary	Oxford hip and knee scores	It is scored between 0 and 48. 48 is the best function.	2 years