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Evaluation of Milk Polar Lipids in Dyslipidemic Adults With Abdominal Obesity

Obesity Clinical Trial

Official title:
Evaluation of Milk Polar Lipids on Lipoprotein Metabolism, Inflammation, and Gut Microbiota in Dyslipidemic Adults With Abdominal Obesity

Clinical Trial Summary

The major objective of this project is to examine whether daily consumption of milk polar lipids (MPLs) influences cardiometabolic risk factors.

Clinical Trial Description

The investigators will conduct a randomized, double-blind, controlled, parallel, intervention study in dyslipidemic adults with abdominal obesity (n = 130). Participants will consume either a control dairy beverage (n = 65) or an MPL-rich dairy beverage (n = 65) for 8 weeks. The investigators plan to evaluate the following 4 specific objectives: 1. Determine the effects of MPLs on serum lipid concentrations and other cardiometabolic risk factors. 2. Evaluate the effects of MPLs on systemic biomarkers of low-grade inflammation. 3. Examine the effects of MPLs on lipoprotein metabolism and lipoprotein particle characteristics. 4. Evaluate the effects of MPLs on gut microbiota, gut permeability markers, and fecal lipids. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05700916
Study type Interventional
Source University of Connecticut
Contact Christopher N Blesso, Ph.D.
Phone 860-486-9049
Email christopher.blesso@uconn.edu
Status Recruiting
Phase Early Phase 1
Start date October 20, 2023
Completion date December 2025
View Details
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