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PET-study on the Role of the Reward System in Weight Loss After Bariatric Surgery — ObesiPET  

Obesity Clinical Trial

Official title:
PET-study on the Role of the Reward System in Weight Loss After Bariatric Surgery

Clinical Trial Summary

Bariatric surgery (BS) is currently the most effective treatment in severe obesity. However, a considerable percentage of patients undergoing BS fail to lose sufficient weight or regain weight after initial weight loss during long-term follow-up, which may be attributed to personality traits and pathological eating behaviour. Previous positron emission tomography (PET) studies have shown reduced dopamine D2 receptor availability in obese patients and upregulation of this availability following successful BS in the brain's reward system. Dopamine D2 receptor availability in patients with unsuccessful BS has not been investigated to date.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05359887
Study type Interventional
Source University Medical Center Groningen
Contact D.L. Marinus Oterdoom, MD
Phone +31503612837
Email d.l.m.oterdoom@umcg.nl
Status Recruiting
Phase N/A
Start date December 1, 2022
Completion date December 31, 2024
View Details
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