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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT05202535
Other study ID # REC/01092 Khowla shah
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date November 15, 2021
Est. completion date March 15, 2022

Study information

Verified date September 2022
Source Riphah International University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

To determine the effect of aerobic exercise training on arterial stiffness and hemodynamics in obese adults. Proper evidence on the effect of aerobic exercise training on both arterial stiffness and hemodynamics are sparsely present in obese adults whereas separate studies were done in mainly hypertensive and cardiovascular disease populations.


Description:

Obese adults always have been trying to improve their quality of life by managing the complications associated with obesity like arterial stiffness and disturbed hemodynamics.


Recruitment information / eligibility

Status Completed
Enrollment 34
Est. completion date March 15, 2022
Est. primary completion date March 15, 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 20 Years to 40 Years
Eligibility Inclusion Criteria: - Body mass index =28 kg/m² - Able to do exercise Exclusion Criteria: - Involved in structured physical activity in last 6 months - History of chronic systemic disease (cardiovascular, pulmonary, and metabolic disease) - Continuous medication use. - MSK or Neurological problems - Pregnant females

Study Design


Related Conditions & MeSH terms


Intervention

Other:
Aerobic exercise training
Hospital-based aerobic exercise training for 15-30 minutes including pre and post-vitals assessment. 3x/week on alternate days for 8 weeks at 40-70% of HR Max
Conventional therapy
Patient education and counseling with diet plan.Walking 3 days15min/day for 8 weeks

Locations

Country Name City State
Pakistan Polyclinic Hospital Islamabad Punjab

Sponsors (1)

Lead Sponsor Collaborator
Riphah International University

Country where clinical trial is conducted

Pakistan, 

References & Publications (2)

Cote AT, Phillips AA, Harris KC, Sandor GG, Panagiotopoulos C, Devlin AM. Obesity and arterial stiffness in children: systematic review and meta-analysis. Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):1038-44. doi: 10.1161/ATVBAHA.114.305062. Epub 2015 Jan 29. Review. — View Citation

Hvidt KN. Blood pressure and arterial stiffness in obese children and adolescents. Dan Med J. 2015 Mar;62(3). pii: B5043. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary Arterial Stiffness Gradual fragmentation and loss of elastin fibers and accumulation of stiffer collagen fibers in the arterial wall. Calculated through Arterial stiffness index. 6 weeks
Primary Hemodynamics Factors that govern blood flow calculated through Rate Pressure Product. 6 weeks
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