Effect of Aerobic Exercise Training in Obese Adults

Obesity Clinical Trial

Official title:

Effect of Aerobic Exercise Training on Arterial Stiffness and Hemodynamics in Obese Adults.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05202535
• Other study ID #: REC/01092 Khowla shah
• Status: Completed
• Phase: N/A
• Start date: November 15, 2021
• Est. completion date: March 15, 2022

Study information

• Verified date: September 2022
• Source: Riphah International University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To determine the effect of aerobic exercise training on arterial stiffness and hemodynamics in obese adults. Proper evidence on the effect of aerobic exercise training on both arterial stiffness and hemodynamics are sparsely present in obese adults whereas separate studies were done in mainly hypertensive and cardiovascular disease populations.

Description:

Obese adults always have been trying to improve their quality of life by managing the complications associated with obesity like arterial stiffness and disturbed hemodynamics.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 34
• Est. completion date: March 15, 2022
• Est. primary completion date: March 15, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 40 Years

Eligibility

Inclusion Criteria:

• Body mass index =28 kg/m²

• Able to do exercise

Exclusion Criteria:

• Involved in structured physical activity in last 6 months

• History of chronic systemic disease (cardiovascular, pulmonary, and metabolic disease)

• Continuous medication use.

• MSK or Neurological problems

• Pregnant females

Related Conditions & MeSH terms

• Obesity

Intervention

Other:
• Aerobic exercise training
Hospital-based aerobic exercise training for 15-30 minutes including pre and post-vitals assessment. 3x/week on alternate days for 8 weeks at 40-70% of HR Max
• Conventional therapy
Patient education and counseling with diet plan.Walking 3 days15min/day for 8 weeks

Locations

Country	Name	City	State
Pakistan	Polyclinic Hospital	Islamabad	Punjab

Sponsors (1)

Lead Sponsor	Collaborator
Riphah International University

Country where clinical trial is conducted

Pakistan, 

References & Publications (2)

Cote AT, Phillips AA, Harris KC, Sandor GG, Panagiotopoulos C, Devlin AM. Obesity and arterial stiffness in children: systematic review and meta-analysis. Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):1038-44. doi: 10.1161/ATVBAHA.114.305062. Epub 2015 Jan 29. Review. — View Citation

Hvidt KN. Blood pressure and arterial stiffness in obese children and adolescents. Dan Med J. 2015 Mar;62(3). pii: B5043. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Arterial Stiffness	Gradual fragmentation and loss of elastin fibers and accumulation of stiffer collagen fibers in the arterial wall. Calculated through Arterial stiffness index.	6 weeks
Primary	Hemodynamics	Factors that govern blood flow calculated through Rate Pressure Product.	6 weeks