Extended Evening Fasting: Metabolic Health and Energy Balance

Obesity Clinical Trial

Official title: The Effect of 4 Days of Extended Evening Fasting on Metabolic Health, Energy Balance and Appetite

Status Recruiting

Clinical Trial Summary

This study will compare metabolic and feeding behaviour responses to 4 days of extended evening fasting vs. a control trial

Clinical Trial Description

Humans have evolved as a diurnal species, internally governed by the circadian system, which dictates our hormone regulation. 'Chrononutrition' is a sub-discipline which combines food timing with circadian physiology. The most popular method of time-restricted feeding in the UK is to skip breakfast. However, data from several meta-analysis have shown that skipping breakfast is associated with weight gain and insulin resistance, likely due to eating later into the evening/night and therefore, out of sync with our circadian rhythm. Recent research has shown that skipping dinner (evening fasting) has improved markers of cardio-metabolic health in clinical populations, although these are typically from longer-term studies. Despite these promising findings, it is not yet known whether these findings are population specific. Therefore, the investigators are interested in examining the metabolic response pre and post intervention to see whether these promising findings can translate into a healthy population. Furthermore, the investigators will be monitoring subjective appetite, energy intake and expenditure to assess whether there is any short-term adaptation to a specific feeding window. ;

Related Conditions & MeSH terms

• Obesity

• NCT number: NCT04924517
• Study type: Interventional
• Source: Nottingham Trent University
• Contact: William Mode, MRes
• Phone: +447484751219
• Email: william_mode@hotmail.co.uk
• Status: Recruiting
• Phase: N/A
• Start date: September 14, 2021
• Completion date: June 14, 2022