Obesity Clinical Trial
Official title:
Effect Of Intermittent Fasting 5: 2 To Waist Circumference, Insulin Resistance And Oxidative Stress Marker In Obese Workers In Jakarta
The world prevalence of obesity in adult population in 2016 was 650 million while in Indonesia, it has increased from 14,8 percent to 21,8 percent in 2018. Obesity is an established risk factors for metabolic and non communicable- diseases. The purpose of this research was to assess the different effect on waist circumference, insulin resistance and oxidative stress marker between fasting (intervention) group and not fasting (control) group after 8 weeks 5:2 intermittent fasting (IF) among obese male workers.
Intermittent fasting is eating pattern in that cycles between periods of fasting and eating.
5:2 intermittent fasting (IF) is a form of time-restricted fasting which no calories are
consumed for at least 14 hours (for 4 am to 6 pm) will done in two non-consecutive days days
per week, followed by ad libitum intake on the remaining days, with water restriction too.
Participants will be distributed to each group by simple randomization. This study will
access the characteristic data, dietary intake and physical activity from the participants.
Anthropometry and blood sample (for insulin resistance (HOMA-IR) and oxidative stress
(malondialdehyde and catalase)) were taken at baseline and at the end of the study.
Participants from each group will gets counseling at the second week of intervention and they
will follow up to 8 weeks with control and evaluation form.
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