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NCT04205318 Clinical Trial

FTO Gene Variants and Diet in Obesity

Obesity Clinical Trial

Official title:
Impact of FTO Gene Variants and Lifestyle Factors on Obesity Traits in a Turkish Population

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04205318
Other study ID # GO15/612-11
Secondary ID
Status Completed
Phase
First received
Last updated
Start date March 1, 2017
Est. completion date December 31, 2018

Study information
Verified date August 2019
Source Hacettepe University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Studies have shown that the effect of fat mass and obesity-associated (FTO) gene on obesity is modulated by lifestyle factors. Hence, we aimed to determine whether two single nucleotide polymorphisms (SNPs) in the FTO gene are associated with obesity and to assess whether these associations were modified by lifestyle factors. The study included 200 obese and 200 non-obese individuals from Turkey. Our study suggests that the effect of the SNPs on obesity traits is likely to be influenced by lifestyle factors in this Turkish population.

Recruitment information / eligibility
Status Completed
Enrollment 400
Est. completion date December 31, 2018
Est. primary completion date February 1, 2018
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 24 Years to 50 Years
Eligibility Inclusion Criteria:

1. attending routine outpatient visits,

2. aged 24 to 50 years,

3. having a BMI = 18.50 kg/m2

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Turkey Zehra Buyuktuncer Ankara

Sponsors (3)
Lead Sponsor Collaborator
Hacettepe University Tubitak, University of Reading

Country where clinical trial is conducted

Turkey, 

Outcome
Type Measure Description Time frame Safety issue
Primary Genetic analysis of two SNPs at FTO gene FTO SNPs rs9939609 and rs10163409 up to 36 weeks
Primary Anthropometric measurements Body mass index, waist circumference, hip circumference, body composition up to 36 weeks
Primary Biochemical measurements lipid profile, glucose, insulin, adiponectin up to 36 weeks
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