Obesity Clinical Trial
— COLOSSOfficial title:
Impact of Bariatric Surgery in Obese Patients With and Without Obstructive Sleep Apnea Syndrome - COLOSS
It has been shown to date that obesity is associated with increased mortality and that weight loss significantly improves cardiovascular risk factors. Among patients receiving bariatric surgery, 30-90% have moderate to severe obstructive sleep apnea (OSA) syndrome. Given the strong associations between OSA and cardiometabolic comorbidities, this project is based on the hypothesis of a lower improvement of cardiovascular risk factors and a higher number of post-surgical complications in OSAS patients.
Status | Recruiting |
Enrollment | 400 |
Est. completion date | May 31, 2026 |
Est. primary completion date | November 30, 2025 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Patient, male or female, aged over 18 - Patient in preparation for bariatric surgery (ring, Sleeve gastrectomy or Bypass) in the center CELIOBE. - Patient affiliated with social security or beneficiary of such a scheme - Patient having signed the free and informed consent Exclusion Criteria: - Patient who has already had bariatric surgery (ring, sleeve gastrectomy or bypass). - Patient already receiving CPAP treatment for sleep apnea syndrome. - Patients with pathology indicating the use of CPAP in self-guided mode (heart failure with altered ejection fraction) for patients diagnosed with OSAS - Patient likely, in the opinion of the investigator, not to be cooperative or respectful of the obligations inherent to participation in the study - Patient suffering from mental pathology does not make possible the collection of a consent. - Protected patient: major under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision - Pregnant, lactating or parturient woman - Patient hospitalized without consent |
Country | Name | City | State |
---|---|---|---|
France | Hôpital privé La Louvière | Lille | Haut De France |
Lead Sponsor | Collaborator |
---|---|
Ramsay Générale de Santé | Dr CODRON |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Hypertension | The primary endpoint is the measurement of Systolic and Diastolic Blood Pressure. | 1 year |
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