Obesity Clinical Trial
Official title:
Effects of Environmental Temperature on Human White Adipose Tissue Thermogenic Capacity
Verified date | July 2019 |
Source | University of Thessaly |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Obesity is characterized by excessive white adipose tissue (WAT) that increases risk for disease. About 700 million adults are obese worldwide, designating the need of reducing excessive WAT in humans and subsequently the risk for disease. For this reason, previous research focused on the thermogenic capacity of white adipocytes in response to cold exposure. The investigators aimed to identify whether human WAT thermogenic activation could alter energy homeostasis and subsequently total body weight. The human WAT thermogenic capacity was assessed via Positron Emission Tomography/Computed Tomography (PET/CT) examination.
Status | Completed |
Enrollment | 20 |
Est. completion date | March 30, 2018 |
Est. primary completion date | January 16, 2018 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | N/A to 50 Years |
Eligibility |
Inclusion Criteria: - healthy adult men - no chronic disease - not being under medication treatment - non-smoking individuals - non-regular exercisers individuals Exclusion Criteria: - non-adult men - women - chronic disease - being under medication treatment - smokers - regular exercisers |
Country | Name | City | State |
---|---|---|---|
Greece | Petros Dinas | Tríkala | Thessaly |
Lead Sponsor | Collaborator |
---|---|
Petros Dinas |
Greece,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Correlation between white adipose tissue activity and environmental temperature. Mean differences in white adipose tissue activity between those participants who were assessed in winter and those who were assessed in summer. | White adipose tissue activity was assessed using a PET/CT examination to calculate the standardized uptake value (SUV) in dorsolumbar region near vertebrae L3 and abdominal region. Daily environmental temperature was obtained in degrees Celsius from the Weather Underground (www.wunderground.com) webpage for the period between January 2017 and February 2019 | An overall of 10 hours of an assessment period that including two hours of cold exposure, 30 minutes of resting energy expenditure and 40 minutes of PET/CT assessments |
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