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Effect of Bariatric Surgery on Brain Insulin Sensitivity

Obesity Clinical Trial

Official title:
Metabolic Characterization of Subjects With Adipositas Before and After Bariatric Surgery

Clinical Trial Summary

Adiposity is associated with prediabetes and type 2 diabetes. In very severe cases of adiposity in combination with type 2 diabetes, bariatric surgery has proven to be a successful therapy option. So far the molecular mechanisms that lead to an improvement of type 2 diabetes after bariatric surgery are not fully understood. It is planned to characterize the metabolic and neuroendocrine changes in subjects before and after bariatric surgery. One special focus of the study is brain insulin resistance, a condition known to be associated with obesity with impact on the brain and whole body metabolism.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03705923
Study type Interventional
Source University Hospital Tuebingen
Contact
Status Terminated
Phase N/A
Start date December 1, 2018
Completion date December 1, 2020
View Details
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