Obesity Clinical Trial
Official title:
The Comparison of PYY, Ghrelin, GLP1, Glucose Level, VAS Level of Satiety, VAS Level of Hunger and Ad Libitum Intake in Obese and Non-Obese Patients After Breakfast With Balanced Macronutrient Composition
Obesity can occur due to an imbalance of energy. This energy balance is greatly influenced by
hunger and satiety. Obese person cannot resist hunger, while non obese can control hunger.
Gut hormones, such as PYY and ghrelin, are associated with appetite and satiety control. This
study's objective is to compare the effect of breakfast with balance composition on gut
hormones, glucose and ad libitum intake four hours after breakfast between obese and non
obese..
The research methodology was used a clinical trial with 18 obese women and 22 non obese women
participants. Subjects were given a balance breakfast (protein 12,4%, carbohydrate 68,2%, fat
22,6%). Gut hormones (PYY, Ghrelin, GLP -1) level , Glucose level and satiety level were
measured at 0, 15, 60, 120, and 180 minutes after breakfast. Ad libitum meal was given four
hours after breakfast and measured after.
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