China Health Big Data

Obesity Clinical Trial

— China biobank  

Official title:

China Nationwide Multi Center Big Data Study on the Quantitative Computed Tomography (QCT) and Health Status of Check -up Population

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03699228
• Other study ID #: jst2018
• Status: Recruiting
• Start date: December 1, 2017
• Est. completion date: December 31, 2023

Study information

• Verified date: November 2022
• Source: Beijing Jishuitan Hospital
• Contact: xiaoguang cheng, md
• Phone: 0086-010-58516947
• Email: xiao65[@]263.net
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

In this nationwide multi center study the investigators combine the low dose chest CT scan data with QCT technology, to measure the BMD of spine, VAT and liver fat in the health check subjects. The aim of this study is to evaluate the performance of QCT in the health check field, and further to evaluate the prevalence of osteoporosis, obesity and liver steatosis in health check population across China.

Description:

Low dose Chest CT scan is the standard for lung cancer in the health check center in China. Quantitative computed tomography (QCT) is utilizing the CT raw data to measure the bone mineral density (BMD), the visceral fat (VAT) and liver fat content in human, which can be widely used in the diagnosis of osteoporosis, the assessment of obesity and liver steatosis. In this nationwide multi center study the investigators combine the low dose chest CT scan data with QCT technology, to measure the BMD of spine, VAT and liver fat in the health check subjects. This study is to evaluate the performance of QCT in the health check field, and further to evaluate the prevalence of osteoporosis, obesity and liver steatosis in health check population across China.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 30000
• Est. completion date: December 31, 2023
• Est. primary completion date: June 30, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 30 Years to 90 Years

Eligibility

Inclusion Criteria:

health check subjects 30-90 years old low dose chest CT scan

Exclusion Criteria:

pregnant women metal implant in the CT scan area

Related Conditions & MeSH terms

• Fatty Liver
• Liver Steatoses
• Obesity
• Osteoporosis

Locations

Country	Name	City	State
China	Beijing Jishuitan hospital	Beijing	Beijing
China	The first affiliated hospital of Guiyang Medical University	Guiyang	Guizhou
China	Hua Shan hospital	Shanghai	Shanghai
China	Shanghai Ruijin hospital	Shanghai	Shanghai
China	Wu Hu Yijishan Hospital	Wu Hu	Anhui
China	The first affiliated hospital of Zhengzhou University	Zhengzhou	Henan

Sponsors (15)

Lead Sponsor

Collaborator

Beijing Jishuitan Hospital

China-Japan Friendship Hospital, Chinese PLA General Hospital, First Affiliated Hospital Xi'an Jiaotong University, Henan Provincial People's Hospital, Huashan Hospital, Nanjing BenQ Hospital, Ruijin Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, The Affiliated Hospital Of Guizhou Medical University, The fifth affiliated hospital of zhong shan university, The First Affiliated Hospital of Zhengzhou University, The renmin hospital of wuhan university, Wu Hu Yijishan hospital, xinan hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The spinal volumetric bone mineral density (vBMD)	The volumetric bone mineral density of L1-2 measured by QCT	2 year
Secondary	The visceral adipose tissue (VAT)	The visceral adipose tissue (VAT) measured by quantitative computed tomography (QCT)	2 year
Secondary	Liver fat	Liver fat measurement by quantitative computed tomography (QCT)	2 years