Determination of the Independent Effects of Beetroot Juice Components, Dietary Nitrate and Antioxidants, on Exercise Tolerance and Health Benefits in Individuals With Obesity

Obesity Clinical Trial

— BEETIT  

Official title:

Determination of the Independent Effects of Beetroot Juice Components, Dietary Nitrate and Antioxidants, on Exercise Tolerance and Health Benefits in Individuals With Obesity

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03545009
• Other study ID #: 300001210
• Status: Completed
• Phase: N/A
• Start date: August 10, 2018
• Est. completion date: August 30, 2020

Study information

• Verified date: September 2021
• Source: University of Alabama at Birmingham
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to assess the effects of acute beetroot juice supplementation on exercise performance and cardiometabolic health in obese individuals with secondary cardiometabolic complications. Additionally, we will determine if the ergogenic health benefits of beetroot juice is due to the nitric oxide compound within the product, the antioxidant compound within the product, or a combination of the two compounds.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 16
• Est. completion date: August 30, 2020
• Est. primary completion date: August 30, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• BMI = 30 kg/m2

• Able to perform exercise testing on a cycle ergometer

Exclusion Criteria:

• Currently taking medications know to affect cardiovascular or respiratory function

• Currently supplementing with an antioxidant compound

• Current smoker

• Currently taking antibiotics

• Not willing to abstain from mouthwash use

• Currently participating in regular physical activity

Related Conditions & MeSH terms

• Exercise
• Metabolic Disease
• Metabolic Diseases
• Obesity

Intervention

Dietary Supplement:
• Sodium Nitrate
70ml sodium nitrate, matched for nitrate concentration in Beetroot Juice arm
• Beetroot Juice no Nitrate
70ml Concentrated Beetroot Juice with nitrate removed
• Beetroot Juice
70ml Concentrated Beetroot Juice

Locations

Country	Name	City	State
United States	University of Alabama at Birmingham	Birmingham	Alabama

Sponsors (1)

Lead Sponsor	Collaborator
University of Alabama at Birmingham

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Time to Exhaustion		A Time to Exhaustion Test will be conducted on each participant a total of four times throughout their participation in the study. This will take place approximately 2.5 hours post ingestion of the dietary supplement they are randomized to at each visit.