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NCT03466697 Clinical Trial

Role of Dopamine Transporter in Glucose Control

Obesity Clinical Trial

Official title:
Role of Dopamine Transporter in Glucose Loading of Healthy Subjects

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03466697
Other study ID # 1707-019-057
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date March 14, 2018
Est. completion date December 20, 2021

Study information
Verified date April 2022
Source Pusan National University Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Healthy subjects will be enrolled in this study. Each subject will be scanned twice with F18-FP-CIT PET which is commercially available. F18-FP-CIT reflects dopamine transporter availability of striatum. Before each PET scan, subject will be injected either glucose or normal saline. Therefore, PET scan will reflect the changes of dopamine transporter availability after the injection of glucose.

Recruitment information / eligibility
Status Completed
Enrollment 40
Est. completion date December 20, 2021
Est. primary completion date December 20, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 20 Years to 40 Years
Eligibility Inclusion Criteria: - healthy subjects Exclusion Criteria: - known neurologic disorder - known drug addiction - known endocrine disorder

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Glucose injection/Normal saline injection
Before each PET scan, subject will be injected either glucose or normal saline.

Locations
Country Name City State
Korea, Republic of Pusan National University Hospital Busan

Sponsors (1)
Lead Sponsor Collaborator
Pusan National University Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome
Type Measure Description Time frame Safety issue
Primary Specific binding ratio of dopamine transporter availabilitiy measured from PET scans Specific binding ratio of dopamine transporter availabilitiy measured from PET scans less than 1 month
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