Profiling the Endocannabinoid Response to Hedonic Eating

Obesity Clinical Trial

— Lekkere trek  

Official title:

Profiling the Endocannabinoid Response to Hedonic Eating

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03113474
• Other study ID #: NL51830.081.14
• Status: Completed
• Phase: N/A
• First received: April 9, 2017
• Last updated: May 22, 2017
• Start date: September 15, 2015
• Est. completion date: October 8, 2015

Study information

• Verified date: May 2017
• Source: Wageningen University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Study into the endocannabinoid response to consuming a palatable versus a neutral food.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 25
• Est. completion date: October 8, 2015
• Est. primary completion date: October 8, 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Healthy (self-report)

• Dutch

• Evaluating one of the used foods as palatable

• Evaluating one of the used foods as neutral

• Hb value between 8.1 and 11.0 mmol/L at screening

Exclusion Criteria:

• restraint eating

• lack of appetite

• difficulties eating/swallowing

• endocrine disorders

• energy restricted diet two months prior to study

• weight change > 5 kg in two months prior to study

• stomach or bowel disease

• taste or smell disorders (self-report)

• not consuming foods used in the study

• smoking > 1 cigarette per day

• drinking > 21 units alcohol per week

Related Conditions & MeSH terms

• Food Preferences
• Obesity

Intervention

Other:
• Food palatability
Food palatability is modulated

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Wageningen University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Endocannainoid levels	To assess changes in endocannabinoid plasma levels prior to, during and after eating a palatable versus a neutral food	prior to, during and two hours after eating
Secondary	Pancreatic polypeptide (pg/ml)	To assess changes in pancreatic polypeptide plasma levels prior to, during and after eating a palatable versus a neutral food	prior to, during and two hours after eating
Secondary	Ghrelin (pg/ml)	To assess changes in ghrelin plasma levels prior to, during and after eating a palatable versus a neutral food	prior to, during and two hours after eating