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Norepinephrine Transporter Imaging in Addiction Disorders

Obesity Clinical Trial

Official title:
Norepinephrine Transporter Imaging in Addiction Disorders

Clinical Trial Summary

In this study we propose to study 24 unmedicated abstinent alcohol dependent patients, 24 obese individuals and 24 individually matched healthy control subjects and determine Norepinephrine Transporter (NET) expression in vivo using (S,S)-[11C]MRB and PET.

Clinical Trial Description

In this study we propose to study 24 unmedicated abstinent alcohol dependent patients, 24 obese individuals and 24 individually matched healthy control subjects and determine NET expression in vivo using (S,S)-[11C]MRB and PET. This will provide novel insight into alterations in pre- and post-synaptic homeostasis in alcoholism and obese people with the goal to explain regulatory processes and their alterations in these disorders. A better understanding of brain mechanisms and contributory stress would have an enormous impact on the public's understanding of the vulnerabilities for these disorders, influence medical and legal response to these problems, could lead to a new understanding of these phenomena, and stimulate a better means of prevention and treatment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01719458
Study type Observational
Source Yale University
Contact
Status Withdrawn
Phase
Start date July 2007
Completion date January 4, 2023
View Details
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